Mortality attributable the CVC‐related infections. · patients with a central venous catheter
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (any severity) compared with placebo/no treatment (low certainty).
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (any severity) compared with cryotherapy (ice chips); GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (moderate to severe) compared with cryotherapy (ice chips); GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (severe) compared with placebo/no treatment (low certainty).
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (severe) compared with cryotherapy (ice chips); GRADE not reported.
1 finding from 1 review
Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy
Chlorhexidine showed no clear difference in oral candidiasis (present) compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy
Chlorhexidine showed no clear difference in oral candidiasis (present) compared with nystatin; GRADE not reported.
1 finding from 1 review
Adverse effects: skin reactions. Reported as attributable to chlorhexidine or soap and water. Data collected during ICU stay · critically ill patients
1 finding from 1 review
Chorioamnionitis Clinical findings · Pregnant women with a gestational age greater than 28 weeks, considered to be in labour receiving chlorhexidine vaginal douching during…
Chlorhexidine vaginal wash showed no clear difference in chorioamnionitis Clinical findings compared with placebo (moderate certainty).
1 finding from 1 review
Postpartum endometritis Clinical findings · Pregnant women with a gestational age greater than 28 weeks, considered to be in labour receiving chlorhexidine vaginal douching during…
Chlorhexidine vaginal wash showed no clear difference in postpartum endometritis Clinical findings compared with placebo (moderate certainty).
1 finding from 1 review
Neonatal sepsis · Pregnant women with a gestational age greater than 28 weeks, considered to be in labour receiving chlorhexidine vaginal douching during…
Chlorhexidine vaginal wash showed no clear difference in neonatal sepsis Clinical findings compared with placebo (low certainty).
1 finding from 1 review
Blood culture confirming neonatal sepsis Clinical findings and confirmation by laboratory · Pregnant women with a gestational age greater than 28 weeks, considered to be in labour receiving chlorhexidine vaginal douching during…
Chlorhexidine vaginal wash showed no clear difference in blood culture confirming neonatal sepsis Clinical findings and… compared with placebo (low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel 1% showed no clear difference in presence of dry socket compared with chlorhexidine gel 0.2%; GRADE not reported.
1 finding from 1 review
Chlorhexidine spray vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether tempered chlorhexidine changes reduction in level of contamination by particles >5 um (droplets) at… compared with non-tempered chlorhexidine (very low certainty).
3 findings from 1 review
MD -10.8 [-15.15, -6.45]
1 study · 20 participants
Very low
MD -17.6 [-23.7, -11.5]
1 study · 20 participants
Very low
MD -15.8 [-22.67, -8.93]
1 study · 20 participants
Very low
Reduction in level of contamination in aerosols (CFU): chlorhexidine vs povidone iodine coolant during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether antimicrobial coolant A (chlorhexidine) changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with antimicrobial coolant B (povidone iodine) (very low certainty).
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU): chlorhexidine vs cinnamon extract coolant during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether antimicrobial coolant A (chlorhexidine) changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with antimicrobial coolant B (cinnamon extract) (very low certainty).
1 finding from 1 review
Surgical site infection · surgical patients
It is very uncertain whether chlorhexidine 4% changes surgical site infection compared with bar soap (very low certainty).
1 finding from 1 review
Adverse events (e.g. ulcers, tooth staining) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review