Changed/stopped drugs due to maternal side‐effects · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug showed no clear difference in changed/stopped drugs due to maternal side‐effects compared with no antihypertensive drugs/placebo (low certainty).
1 finding from 1 review
All‐cause mortality · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
Antihypertensive drug therapy showed no clear difference in all‐cause mortality compared with control (low certainty).
1 finding from 1 review
Cardiovascular mortality and morbidity Mean duration of 3.7 years · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
Antihypertensive drug therapy may leads to lower total cardiovascular mortality + morbidity compared with control (low certainty).
1 finding from 1 review
Cerebrovascular mortality + morbidity · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
Antihypertensive drug therapy may leads to lower cerebrovascular mortality + morbidity compared with control (low certainty).
1 finding from 1 review
Coronary heart disease mortality + morbidity · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
Antihypertensive drug therapy showed no clear difference in coronary heart disease mortality + morbidity compared with control (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
It is very uncertain whether antihypertensive drug therapy changes withdrawal due to adverse events compared with control (very low certainty).
1 finding from 1 review
Decrease in SBP5 at end of 1 year · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
1 finding from 1 review
Decrease in DBP6 at end of 1 year · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
1 finding from 1 review
Maternal · women with mild to moderate hypertension during pregnancy
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Severe pre‐eclampsia · women with mild to moderate hypertension during pregnancy
It is very uncertain whether any antihypertensive drug changes severe pre‐eclampsia compared with no antihypertensive drugs/placebo (very low certainty).
1 finding from 1 review
Eclampsia · women with mild to moderate hypertension during pregnancy
It is very uncertain whether any antihypertensive drug changes eclampsia compared with no antihypertensive drugs/placebo (very low certainty).
1 finding from 1 review
Elective delivery (induction of labour + elective caesarean section) · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug showed no clear difference in elective delivery (induction of labour + elective caesarean section) compared with no antihypertensive drugs/placebo (moderate certainty).
1 finding from 1 review
Fetal/neonatal/infant · women with mild to moderate hypertension during pregnancy
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Admission to neonatal or intensive care nursery · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug showed no clear difference in admission to neonatal or intensive care nursery compared with no antihypertensive drugs/placebo (low certainty).
1 finding from 1 review
Severe hypertension · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug probably leads to lower severe hypertension compared with no antihypertensive drugs/placebo (moderate certainty).
1 finding from 1 review
Proteinuria/pre‐eclampsia · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug showed no clear difference in proteinuria/pre‐eclampsia compared with no antihypertensive drugs/placebo (low certainty).
1 finding from 1 review
Total reported fetal or neonatal deaths (including miscarriage) · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug showed no clear difference in total reported fetal or neonatal deaths (including miscarriage) compared with no antihypertensive drugs/placebo (moderate certainty).
1 finding from 1 review
Small‐for‐gestational age · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug showed no clear difference in small‐for‐gestational age compared with no antihypertensive drugs/placebo (moderate certainty).
1 finding from 1 review
Preterm birth · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug showed no clear difference in preterm birth (< 37 weeks) compared with no antihypertensive drugs/placebo (moderate certainty).
1 finding from 1 review
Maternal death · women with mild to moderate hypertension during pregnancy
It is very uncertain whether any antihypertensive drug changes maternal death compared with no antihypertensive drugs/placebo (very low certainty).
1 finding from 1 review