Question · asked by 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo: Total reported fetal or neonatal deaths (including miscarriage)

Any antihypertensive drug showed no clear difference in total reported fetal or neonatal deaths (including miscarriage) compared with no antihypertensive drugs/placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Any antihypertensive drug vs no antihypertensive drugs/placebo
Total reported fetal or neonatal deaths (including miscarriage) · women with mild to moderate hypertension during pregnancy
Any antihypertensive drug showed no clear difference in total reported fetal or neonatal deaths (including miscarriage) compared with no antihypertensive drugs/placebo (moderate certainty).
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy (2018) · Cochrane Headline outcomes only
RR 0.72 [0.5, 1.04]29 studies · 3365 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.