Question · asked by 1 review
Any antihypertensive drug vs no antihypertensive drugs/placebo: Severe pre‐eclampsia
- Population
- women with mild to moderate hypertension during pregnancy
- Intervention
- Any antihypertensive drug
- Comparison
- no antihypertensive drugs/placebo
- Outcome
- Severe pre‐eclampsia
It is very uncertain whether any antihypertensive drug changes severe pre‐eclampsia compared with no antihypertensive drugs/placebo (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Any antihypertensive drug vs no antihypertensive drugs/placebo Severe pre‐eclampsia · women with mild to moderate hypertension during pregnancy It is very uncertain whether any antihypertensive drug changes severe pre‐eclampsia compared with no antihypertensive drugs/placebo (very low certainty). Antihypertensive drug therapy for mild to moderate hypertension during pregnancy (2018) · Cochrane Headline outcomes only | RR 0.56 [0.15, 2.02] | 3 studies · 416 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.