Benefits and harms of CSF plus antibiotics showed no clear difference in overall mortality compared with antibiotics alone (low certainty).
Benefits and harms of CSF plus antibiotics showed no clear difference in infection‐related mortality compared with antibiotics alone (low certainty).
Benefits and harms of CSF plus antibiotics may leads to lower people hospitalized for > 10 days compared with antibiotics alone (low certainty).
Benefits and harms of CSF plus antibiotics showed no clear difference in duration of grade IV neutropenia (lower values signify better… compared with antibiotics alone (low certainty).
Benefits and harms of CSF plus antibiotics showed no clear difference in time to recovery from fever (lower values signify better outcomes) compared with antibiotics alone (low certainty).
Benefits and harms of CSF plus antibiotics showed no clear difference in time to withdrawal from ATB (lower values signify better outcomes) compared with antibiotics alone (low certainty).
Benefits and harms of CSF plus antibiotics showed no clear difference in deep vein thrombosis compared with antibiotics alone (low certainty).
Mortality with anti‐gram‐positive antibiotics showed no clear difference in overall mortality compared with placebo (moderate certainty).
It is very uncertain whether adverse events with anti‐gram‐positive antibiotics changes any adverse events compared with placebo (very low certainty).
Treatment failure with anti‐gram‐positive antibiotics showed no clear difference in overall failure (disregarding modifications) compared with placebo (low certainty).
It is very uncertain whether treatment failure with anti‐gram‐positive antibiotics changes failure, modifications included compared with placebo (very low certainty).
Summary of findings: antibiotics leads to lower all cause mortality compared with placebo or no intervention (high certainty).
Summary of findings: antibiotics probably leads to lower febrile patients and episodes compared with placebo or no intervention (moderate certainty).
Summary of findings: antibiotics leads to lower bacteraemia compared with placebo or no intervention (high certainty).
Early discontinuation of antibiotic treatment showed no clear difference in mortality compared with treatment until neutropenia resolution (low certainty).
It is very uncertain whether early discontinuation of antibiotic treatment changes clinical failure compared with treatment until neutropenia resolution (very low certainty).
It is very uncertain whether early discontinuation of antibiotic treatment changes any bacteraemia compared with treatment until neutropenia resolution (very low certainty).