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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

531 questions in 102 reviews · Gynaecology and Fertility

current versions
No studies 531 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ Metformin + megestrol vs megestrol
Abnormal uterine bleeding ‐ not measured · endometrial hyerplasia
Metformin for endometrial hyperplasia (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Metformin + megestrol vs megestrol
Health‐related quality of life (HRQoL) ‐ not measured · endometrial hyerplasia
Metformin for endometrial hyperplasia (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Metformin + levonorgestrel (intrauterine system) vs levonorgestrel intrauterine system
Recurrence of endometrial hyperplasia ‐ not reported · endometrial hyperplasia
Metformin for endometrial hyperplasia (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Metformin vs megestrol
Health‐related quality of life (HRQoL) ‐ not measured · endometrial hyperplasia
Metformin for endometrial hyperplasia (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Metformin vs megestrol
Adverse effects during treatment ‐ not reported · endometrial hyperplasia
Metformin for endometrial hyperplasia (2024) · Cochrane
no estimate extractedNRNo studies
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Adverse events · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Adverse events · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
NSAID vs combined OCP
Pain improvement · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
NSAID vs combined OCP
Adverse events · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
NSAID vs combined OCP
Requirement for additional medication · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
NSAID vs combined OCP
Absence from work or school · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
Combined low‐dose OCP vs another combined low‐dose OCP
Requirement for additional medication · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
IVF vs expectant management
Multiple pregnancy rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
no estimate extractedNRNo studies
IVF vs expectant management
OHSS rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
no estimate extractedNRNo studies
IVF vs expectant management
Miscarriage rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
no estimate extractedNRNo studies
IVF vs unstimulated IUI
OHSS rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
no estimate extractedNRNo studies
Laparoscopic hysterectomy vs vaginal hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Robotic hysterectomy vs laparoscopic hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Robotic hysterectomy vs laparoscopic hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Robotic hysterectomy vs laparoscopic hysterectomy
Intra‐operative visceral injury (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Robotic hysterectomy vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
V‐NOTES vs laparoscopic hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
V‐NOTES vs laparoscopic hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
V‐NOTES vs laparoscopic hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
V‐NOTES vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Statin vs placebo
Resumption of spontaneous ovulation · women with polycystic ovary syndrome not actively trying to conceive
Statins for women with polycystic ovary syndrome not actively trying to conceive (2023) · Cochrane
no estimate extractedNRNo studies
Statin vs metformin
Resumption of spontaneous ovulation · women with polycystic ovary syndrome not actively trying to conceive
Statins for women with polycystic ovary syndrome not actively trying to conceive (2023) · Cochrane
no estimate extractedNRNo studies
Statin vs metformin
Adverse effects · women with polycystic ovary syndrome not actively trying to conceive
Statins for women with polycystic ovary syndrome not actively trying to conceive (2023) · Cochrane
no estimate extractedNRNo studies
Statin vs placebo
Improvement in hirsutism · women with polycystic ovary syndrome not actively trying to conceive
Statins for women with polycystic ovary syndrome not actively trying to conceive (2023) · Cochrane
no estimate extractedNRNo studies
Statin vs placebo
Improvement in acne severity · women with polycystic ovary syndrome not actively trying to conceive
Statins for women with polycystic ovary syndrome not actively trying to conceive (2023) · Cochrane
no estimate extractedNRNo studies
Hormonal therapy vs placebo or no intervention
Estrogen + progestogens · symptomatic or early postmenopausal womena
Hormone therapy for sexual function in perimenopausal and postmenopausal women (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Quality of life – not reported · couples trying to conceive
Timed intercourse for couples trying to conceive (2023) · Cochrane
no estimate extractedNRNo studies
GnRHas vs no treatment
No studies included for any outcomes · Women with endometriosis
Gonadotropin‐releasing hormone analogues for endometriosis (2023) · Cochrane
no estimate extractedNRNo studies
GnRHas vs intra‐uterine progestogens device
No studies included with only low risk of bias · Women with pain due to endometriosis
Gonadotropin‐releasing hormone analogues for endometriosis (2023) · Cochrane
no estimate extractedNRNo studies
GnRHas vs analgesics
No studies included for any outcomes · Women with pain due to endometriosis
Gonadotropin‐releasing hormone analogues for endometriosis (2023) · Cochrane
no estimate extractedNRNo studies
Blastocyst‐stage vs cleavage‐stage embryo transfer
Outcomes per couple · women and couples with subfertility
Cleavage‐stage versus blastocyst‐stage embryo transfer in assisted reproductive technology (2022) · Cochrane
no estimate extractedNRNo studies
Low vs high 17ß‐oestradiol dose
Endometrial histology · young women with Turner syndrome who have completed pubertal induction
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Low vs high 17ß‐oestradiol dose
Uterine perfusion · young women with Turner syndrome who have completed pubertal induction
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Low vs high 17ß‐oestradiol dose
Reproductive outcomes · young women with Turner syndrome who have completed pubertal induction
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Oral vs vaginal administration of oestradiol and dydrogesterone
Endometrial histology · women with premature ovarian insufficiency (POI) awaiting oocyte donation
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Oral vs vaginal administration of oestradiol and dydrogesterone
Uterine perfusion · women with premature ovarian insufficiency (POI) awaiting oocyte donation
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies
Conjugated oral oestrogens vs transdermal 17ß‐estradiol
Endometrial thickness · girls with Turner syndrome who were treated with prepubertal growth hormone
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency (2022) · Cochrane
no estimate extractedNRNo studies