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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
57 questions in 13 reviews · Drugs and Alcohol
current versionsNo studies 57 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Summary of findings table – disulfiram vs naltrexone Continuous abstinence from cocaine (number of participants who had achieved and maintained abstinence for at least three weeks at the end of treatment) · people with cocaine dependence Disulfiram for the treatment of cocaine dependence (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table – disulfiram vs naltrexone Point abstinence (number of participants who were abstinent at the end of the treatment) · people with cocaine dependence Disulfiram for the treatment of cocaine dependence (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table – disulfiram vs naltrexone Any adverse events (number of participants who experienced at least one adverse event) · people with cocaine dependence Disulfiram for the treatment of cocaine dependence (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Any psychosocial intervention vs treatment Continuous abstinence, longest · adults with stimulant use disorder Psychosocial interventions for stimulant use disorder (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Any psychosocial intervention vs treatment Adverse events ‐ not measured · stopping or reducing alcohol consumption during pregnancy Psychosocial and medication interventions to stop or reduce alcohol consumption during pregnancy (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Any psychosocial intervention vs treatment Withdrawal signs and symptoms ‐ not measured · stopping or reducing alcohol consumption during pregnancy Psychosocial and medication interventions to stop or reduce alcohol consumption during pregnancy (2024) · Cochrane | no estimate extracted | NR | No studies |
Motivational interviewing vs assessment and feedback Extent of substance use post‐intervention · people with substance use (adults, young adults, adolescents) Motivational interviewing for substance use reduction (2023) · Cochrane | no estimate extracted | NR | No studies |
Motivational interviewing vs assessment and feedback Readiness to change · people with substance use (adults, young adults, adolescents) Motivational interviewing for substance use reduction (2023) · Cochrane | no estimate extracted | NR | No studies |
Motivational interviewing vs assessment and feedback Retention in treatment · people with substance use (adults, young adults, adolescents) Motivational interviewing for substance use reduction (2023) · Cochrane | no estimate extracted | NR | No studies |
Pharmacologic intervention vs another pharmacologic intervention Harmful alcohol use ‐ not measured · individuals with alcohol use disorder Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries (2023) · Cochrane | no estimate extracted | NR | No studies |
Pharmacologic intervention vs another pharmacologic intervention Harmful alcohol use ‐ not measured · individuals with alcohol use disorder Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries (2023) · Cochrane | no estimate extracted | NR | No studies |
Music therapy plus standard care vs active intervention plus standard care Retention in treatment · people with substance use disorders Music therapy for people with substance use disorders (2022) · Cochrane | no estimate extracted | NR | No studies |
Music therapy plus standard care vs active intervention plus standard care Serious adverse events · people with substance use disorders Music therapy for people with substance use disorders (2022) · Cochrane | no estimate extracted | NR | No studies |
Music therapy plus standard care vs standard care alone Serious adverse events · people with substance use disorders Music therapy for people with substance use disorders (2022) · Cochrane | no estimate extracted | NR | No studies |
Methadone vs oral slow‐release morphine APGAR score (APGAR score ) · opiate‐dependent pregnant women Maintenance agonist treatments for opiate‐dependent pregnant women (2020) · Cochrane | no estimate extracted | NR | No studies |
Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (manualized) vs a different type of TSF Alcohol‐related consequences · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence Alcoholics Anonymous and other 12‐step programs for alcohol use disorder (2020) · Cochrane | no estimate extracted | NR | No studies |
Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (non‐manualized) vs a different type of TSF Drinking intensity · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence Alcoholics Anonymous and other 12‐step programs for alcohol use disorder (2020) · Cochrane | no estimate extracted | NR | No studies |
Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (non‐manualized) vs a different type of TSF Alcohol‐related consequences · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence Alcoholics Anonymous and other 12‐step programs for alcohol use disorder (2020) · Cochrane | no estimate extracted | NR | No studies |
Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (non‐manualized) vs a different type of TSF Alcohol addiction severity · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence Alcoholics Anonymous and other 12‐step programs for alcohol use disorder (2020) · Cochrane | no estimate extracted | NR | No studies |
Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (non‐manualized) vs a different type of TSF Alcohol‐related consequences · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence Alcoholics Anonymous and other 12‐step programs for alcohol use disorder (2020) · Cochrane | no estimate extracted | NR | No studies |
Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (non‐manualized) vs other clinical interventions Alcohol‐related consequences · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence Alcoholics Anonymous and other 12‐step programs for alcohol use disorder (2020) · Cochrane | no estimate extracted | NR | No studies |
Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (non‐manualized) vs other clinical interventions Alcohol addiction severity · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence Alcoholics Anonymous and other 12‐step programs for alcohol use disorder (2020) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs placebo AW seizures · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs diazepam AW seizures · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs diazepam AW delirium · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs diazepam Global improvement · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs diazepam Craving · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs diazepam Severe AEs · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs chlordiazepoxide AW seizures · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs placebo AW delirium · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs chlordiazepoxide AW delirium · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs chlordiazepoxide Craving · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs chlordiazepoxide Severe AEs · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs placebo Global improvement · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs placebo Craving · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs placebo AEs · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs placebo Severe AEs · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs placebo Dropouts · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Baclofen vs placebo Dropouts due to AEs · people with alcohol withdrawal Baclofen for alcohol withdrawal (2019) · Cochrane | no estimate extracted | NR | No studies |
Family/parent interventions vs control Adverse events · parents/children Family‐based prevention programmes for alcohol use in young people (2019) · Cochrane | no estimate extracted | NR | No studies |
Family/parent and adolescent interventions vs adolescent only interventions Adverse events · parents and children Family‐based prevention programmes for alcohol use in young people (2019) · Cochrane | no estimate extracted | NR | No studies |
Extended intervention vs brief intervention Frequency of binge drinking (no. binges/wk) at 12 months ‐ not measured · people with hazardous or harmful alcohol consumption Effectiveness of brief alcohol interventions in primary care populations (2018) · Cochrane | no estimate extracted | NR | No studies |
Digital intervention vs face‐to‐face intervention Adverse events · s Personalised digital interventions for reducing hazardous and harmful alcohol consumption in… (2017) · Cochrane | no estimate extracted | NR | No studies |
Digital intervention vs no or minimal intervention Adverse events · s Personalised digital interventions for reducing hazardous and harmful alcohol consumption in… (2017) · Cochrane | no estimate extracted | NR | No studies |
Digital intervention vs face‐to‐face intervention Intensity of drinking (g/drinking day) · s Personalised digital interventions for reducing hazardous and harmful alcohol consumption in… (2017) · Cochrane | no estimate extracted | NR | No studies |
Alcohol ban vs no ban Delayed age of initiation of alcohol use ‐ not reported · General population Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane | no estimate extracted | NR | No studies |
Alcohol ban vs no ban Reduction in alcohol‐related injuries or accidents ‐ not reported · General population Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane | no estimate extracted | NR | No studies |
Alcohol ban vs no ban Reduction in individual spending on alcohol ‐ not reported · General population Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane | no estimate extracted | NR | No studies |
Alcohol ban vs no ban Loss of revenue from alcohol industry ‐ not reported · General population Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane | no estimate extracted | NR | No studies |
Alcohol ban vs no ban Loss of advertising revenue ‐ not reported · General population Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane | no estimate extracted | NR | No studies |