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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

504 questions in 57 reviews · Kidney and Transplant

current versions
No studies 504 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
High vs with low‐dose potassium binder
Cardiovascular death · people with CKD
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease (2020) · Cochrane
no estimate extractedNRNo studies
High vs with low‐dose potassium binder
Cardiac arrhythmia · people with CKD
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease (2020) · Cochrane
no estimate extractedNRNo studies
High vs with low‐dose potassium binder
HRQoL · people with CKD
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease (2020) · Cochrane
no estimate extractedNRNo studies
High vs with low‐dose potassium binder
Serum potassium · people with CKD
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease (2020) · Cochrane
no estimate extractedNRNo studies
Potassium binder vs placebo
Cardiac arrhythmia · people with CKD (including haemodialysis)
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease (2020) · Cochrane
no estimate extractedNRNo studies
Calcium polystyrene sulphonate (CPS) vs sodium polystyrene sulphonate (SPS)
Death (any cause) · people with CKD
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease (2020) · Cochrane
no estimate extractedNRNo studies
Calcium polystyrene sulphonate (CPS) vs sodium polystyrene sulphonate (SPS)
Cardiovascular death · people with CKD
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease (2020) · Cochrane
no estimate extractedNRNo studies
Calcium polystyrene sulphonate (CPS) vs sodium polystyrene sulphonate (SPS)
Cardiac arrhythmia · people with CKD
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease (2020) · Cochrane
no estimate extractedNRNo studies
Extended vs short duration antibiotics
Adverse reactions · preventing post‐surgical site infections in solid organ transplant recipients
Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients (2020) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs no antibiotics
Adverse reactions · solid organ transplant recipients
Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients (2020) · Cochrane
no estimate extractedNRNo studies
Surgical reimplantation of ureters plus antibiotics vs antibiotics alone
Number of UTI with microbial resistance (resistant organisms) · primary VUR
Interventions for primary vesicoureteric reflux (2019) · Cochrane
no estimate extractedNRNo studies
Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux
New renal parenchymal defects on DMSA scan (kidney injury) · primary VUR
Interventions for primary vesicoureteric reflux (2019) · Cochrane
no estimate extractedNRNo studies
Probiotics vs antibiotic prophylaxis
Resolution of VUR · primary VUR
Interventions for primary vesicoureteric reflux (2019) · Cochrane
no estimate extractedNRNo studies
Probiotics vs antibiotic prophylaxis
Adverse events · primary VUR
Interventions for primary vesicoureteric reflux (2019) · Cochrane
no estimate extractedNRNo studies
Target of rapamycin inhibitors (TOR‐I) vs calcineurin inhibitors (CNI): main outcomes
Outcomes (up to 2 years for primary outcomes) · primary immunosuppression in kidney transplant recipients
Target of rapamycin inhibitors (TOR‐I; sirolimus and everolimus) for primary immunosuppression in kidney… (2019) · Cochrane
no estimate extractedNRNo studies
Target of rapamycin inhibitors (TOR‐I) vs antimetabolites: primary outcomes
Outcomes (up to 2 years for primary outcomes) · primary immunosuppression in kidney transplant recipients
Target of rapamycin inhibitors (TOR‐I; sirolimus and everolimus) for primary immunosuppression in kidney… (2019) · Cochrane
no estimate extractedNRNo studies
Target of rapamycin inhibitors (TOR‐I) vs antimetabolites: secondary outcomes
Outcomes (up to 2 years for secondary outcomes) · primary immunosuppression in kidney transplant recipients
Target of rapamycin inhibitors (TOR‐I; sirolimus and everolimus) for primary immunosuppression in kidney… (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcomes (up to 2 years for primary outcomes) · primary immunosuppression in kidney transplant recipients
Target of rapamycin inhibitors (TOR‐I; sirolimus and everolimus) for primary immunosuppression in kidney… (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcomes (up to 2 years for secondary outcomes) · primary immunosuppression in kidney transplant recipients
Target of rapamycin inhibitors (TOR‐I; sirolimus and everolimus) for primary immunosuppression in kidney… (2019) · Cochrane
no estimate extractedNRNo studies
Target of rapamycin inhibitors (TOR‐I) vs calcineurin inhibitors (CNI): secondary outcomes
Outcomes (up to 2 years for secondary outcomes) · primary immunosuppression in kidney transplant recipients
Target of rapamycin inhibitors (TOR‐I; sirolimus and everolimus) for primary immunosuppression in kidney… (2019) · Cochrane
no estimate extractedNRNo studies
Cognitive‐behavioural therapy vs usual care
Major depression Mini International Neuropsychiatric Interview (MINI) (median · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Counselling vs usual care
HRQoL Kidney Disease Quality of Life (KDQOL‐36) (median · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Counselling vs usual care
Anxiety · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Counselling vs usual care
Withdrawal from dialysis · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Counselling vs usual care
Withdrawal from intervention (median · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Exercise vs usual care
Anxiety Hospital Anxiety and Depression Scale (HADS) (median · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Exercise vs usual care
Withdrawal from dialysis · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Exercise vs usual care
Withdrawal from intervention · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Exercise vs usual care
Death (any cause) · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Relaxation techniques vs usual care
Major depression · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Relaxation techniques vs usual care
HRQoL Investigators measured health‐related quality of life using the Health Status Questionnaire Short Form (SF‐36) (median · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Relaxation techniques vs usual care
Anxiety · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Relaxation techniques vs usual care
Withdrawal from dialysis · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Relaxation techniques vs usual care
Withdrawal from intervention · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Relaxation techniques vs usual care
Death (any cause) · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Spiritual practice vs usual care
Major depression · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Spiritual practice vs usual care
Health‐related quality of life Health Status Questionnaire Short Form (SF‐36) (median · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Spiritual practice vs usual care
Anxiety Brief Symptom Inventory (BSI) (median · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Spiritual practice vs usual care
Withdrawal from dialysis · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Spiritual practice vs usual care
Withdrawal from intervention · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Spiritual practice vs usual care
Death (any cause) · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Cognitive‐behavioural therapy vs usual care
Anxiety Beck Anxiety Inventory (BAI) (median · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Cognitive‐behavioural therapy vs usual care
Withdrawal from dialysis · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Cognitive‐behavioural therapy vs usual care
Withdrawal from intervention · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Counselling vs usual care
Major depression · people with ESKD
Psychosocial interventions for preventing and treating depression in dialysis patients (2019) · Cochrane
no estimate extractedNRNo studies
Human albumin infusion plus furosemide vs glucose
Quality of life · patients of all ages with oedema due to nephrotic syndrome
Human albumin infusion for treating oedema in people with nephrotic syndrome (2019) · Cochrane
no estimate extractedNRNo studies
Low dialysate [Na+] (< 138 mM) vs high dialysate [Na+] (> 140 mM)
Antihypertensive medication · chronic HD
Low dialysate sodium levels for chronic haemodialysis (2019) · Cochrane
no estimate extractedNRNo studies
Hypothermic machine perfusion vs static cold storage
One year graft survival · deceased donor kidney transplantation
Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation (2019) · Cochrane
no estimate extractedNRNo studies
Isothermal dialysate vs thermoneutral dialysate
Death (all causes) · patients requiring haemodialysis
Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease… (2019) · Cochrane
no estimate extractedNRNo studies
Isothermal dialysate vs thermoneutral dialysate
Acute coronary syndrome · patients requiring haemodialysis
Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease… (2019) · Cochrane
no estimate extractedNRNo studies