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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

555 questions in 79 reviews · Musculoskeletal

current versions
No studies 555 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty
Mortality · people with knee osteoarthritis
Osteotomy for treating knee osteoarthritis (2014) · Cochrane
no estimate extractedNRNo studies
Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty
Reoperation rate · people with knee osteoarthritis
Osteotomy for treating knee osteoarthritis (2014) · Cochrane
no estimate extractedNRNo studies
Other types of high tibial osteotomy (aHTO) vs closing wedge high tibial osteotomy (CW‐HTO)
Health‐related quality of life measures · people with knee osteoarthritis
Osteotomy for treating knee osteoarthritis (2014) · Cochrane
no estimate extractedNRNo studies
Other types of high tibial osteotomy (aHTO) vs closing wedge high tibial osteotomy (CW‐HTO)
Mortality · people with knee osteoarthritis
Osteotomy for treating knee osteoarthritis (2014) · Cochrane
no estimate extractedNRNo studies
Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty
Pain · people with knee osteoarthritis
Osteotomy for treating knee osteoarthritis (2014) · Cochrane
no estimate extractedNRNo studies
Sulfasalazine vs placebo
Mean improvement in Bath ankylosing spondylitis disease activity index (BASDAI) ‐ not reported · Patients with ankylosing spondylitis
Sulfasalazine for ankylosing spondylitis (2014) · Cochrane
no estimate extractedNRNo studies
Sulfasalazine vs placebo
Mean improvement in Bath ankylosing spondylitis function index (BASFI) ‐ not reported · Patients with ankylosing spondylitis
Sulfasalazine for ankylosing spondylitis (2014) · Cochrane
no estimate extractedNRNo studies
Sulfasalazine vs placebo
Mean improvement in Bath ankylosing spondylitis metrology index (BASMI) ‐ not reported · Patients with ankylosing spondylitis
Sulfasalazine for ankylosing spondylitis (2014) · Cochrane
no estimate extractedNRNo studies
Sulfasalazine vs placebo
Radiographic progress ‐ not reported · Patients with ankylosing spondylitis
Sulfasalazine for ankylosing spondylitis (2014) · Cochrane
no estimate extractedNRNo studies
Diacerein vs placebo
Quality of Life not measured · participants with osteoarthritis
Diacerein for osteoarthritis (2014) · Cochrane
no estimate extractedNRNo studies
Diacerein vs placebo
Total number of serious adverse events not measured · participants with osteoarthritis
Diacerein for osteoarthritis (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol 100‐300 mg daily vs febuxostat 80 mg daily
Pain reduction ‐ not measured · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol 100‐300 mg daily vs febuxostat 80 mg daily
Function ‐ not measured · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol 100‐300 mg daily vs febuxostat 80 mg daily
Tophus regression · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs benzbromarone
Pain reduction ‐ not measured · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs benzbromarone
Function ‐ not measured · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs benzbromarone
Tophus regression ‐ not reported · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs benzbromarone
Serious adverse effects · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Function · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Tophus regression · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events not reported · people with osteoarthritis of the hip
Exercise for osteoarthritis of the hip (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events not reported · people with osteoarthritis of the hip
Exercise for osteoarthritis of the hip (2014) · Cochrane
no estimate extractedNRNo studies
SMP vs Attention control
Positive and active engagement in life —not measured · patients with osteoarthritis
Self‐management education programmes for osteoarthritis (2014) · Cochrane
no estimate extractedNRNo studies
Rilonacept vs indomethacin
Functional disability ‐ not measured · acute gout
Interleukin‐1 inhibitors for acute gout (2014) · Cochrane
no estimate extractedNRNo studies
Rilonacept vs indomethacin
Health‐related quality of life ‐ not measured · acute gout
Interleukin‐1 inhibitors for acute gout (2014) · Cochrane
no estimate extractedNRNo studies
Rilonacept vs indomethacin
Participant global assessment of treatment success ‐ not measured · acute gout
Interleukin‐1 inhibitors for acute gout (2014) · Cochrane
no estimate extractedNRNo studies
Canakinumab vs triamcinolone acetonide
Functional disability ‐ not measured · acute gout
Interleukin‐1 inhibitors for acute gout (2014) · Cochrane
no estimate extractedNRNo studies
Canakinumab vs triamcinolone acetonide
Health‐related quality of life ‐ not measured · acute gout
Interleukin‐1 inhibitors for acute gout (2014) · Cochrane
no estimate extractedNRNo studies
Rilonacept vs indomethacin
Inflammation ‐ not measured · acute gout
Interleukin‐1 inhibitors for acute gout (2014) · Cochrane
no estimate extractedNRNo studies
Benzbromarone vs probenecid
Pain Reduction ‐ not measured · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Benzbromarone vs probenecid
Function ‐ not measured · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Benzbromarone vs probenecid
Tophus regression ‐ not measured · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Probenecid vs allopurinol
Serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) ‐ not measured · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Probenecid vs allopurinol
Withdrawal due to adverse events ‐ not reported · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Probenecid vs allopurinol
Total adverse events ‐ not reported · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Probenecid vs allopurinol
Pain reduction ‐ not measured · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Probenecid vs allopurinol
Function ‐ not measured · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Probenecid vs allopurinol
Tophus regression ‐ not reported · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Benzbromarone vs allopurinol
Pain reduction ‐ not measured · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Benzbromarone vs allopurinol
Function ‐ not measured · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Benzbromarone vs allopurinol
Tophus regression ‐ not reported · people with chronic gout
Uricosuric medications for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy and exercise vs glucocorticoid injection
Participant‐reported pain relief ≥ 30% · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy, exercise, electrotherapy and placebo injection vs glucocorticoid injection
Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy, exercise, electrotherapy and placebo injection vs glucocorticoid injection
Active shoulder abduction · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy, exercise, electrotherapy and placebo injection vs glucocorticoid injection
Adverse events · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy, exercise, electrotherapy and placebo injection vs placebo injection
Participant‐reported pain relief ≥ 30% · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy, exercise, electrotherapy and placebo injection vs placebo injection
Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy, exercise, electrotherapy and placebo injection vs placebo injection
Active shoulder abduction · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy, exercise, electrotherapy and placebo injection vs placebo injection
Adverse events · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies
Combination of manual therapy, exercise, electrotherapy and glucocorticoid injection vs glucocorticoid injection
Participant‐reported pain relief ≥ 30% · patients with adhesive capsulitis (frozen shoulder)
Manual therapy and exercise for adhesive capsulitis (frozen shoulder) (2014) · Cochrane
no estimate extractedNRNo studies