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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
249 questions in 68 reviews · Airways
current versionsNo studies 249 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intermittent LTRA vs placebo Serious adverse events · episodic viral wheeze in children Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children (2015) · Cochrane | no estimate extracted | NR | No studies |
Maintenance LTRA vs placebo Serious adverse events · episodic viral wheeze in children Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children (2015) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Hospitalisations · individuals with stable bronchiectasis Airway clearance techniques for bronchiectasis (2015) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse events (AEs) · individuals with stable bronchiectasis Airway clearance techniques for bronchiectasis (2015) · Cochrane | no estimate extracted | NR | No studies |
Bromhexine vs placebo Frequency and duration of exacerbations · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
RhDNase vs placebo Adverse events · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
RhDNase vs placebo Health‐related quality of life · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Erdosteine vs no treatment Frequency and duration of exacerbations · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Erdosteine vs no treatment Hospitalisations for infective exacerbations · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Erdosteine vs no treatment Adverse events · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Erdosteine vs no treatment Health‐related quality of life · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Bromhexine vs placebo Hospitalisations · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Erdosteine vs no treatment Deaths · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Bromhexine vs placebo Health‐related quality of life · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Bromhexine vs placebo Deaths · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
RhDNase vs placebo Frequency and duration of exacerbations · patients with bronchiectasis Mucolytics for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Inhaled mannitol vs placebo Mortality · patients with bronchiectasis Inhaled hyperosmolar agents for bronchiectasis (2014) · Cochrane | no estimate extracted | NR | No studies |
Non‐invasive ventilation during exercise training vs exercise training alone or exercise training with sham non‐invasive ventilation Physical activity: not measured · people with chronic obstructive pulmonary disease Non‐invasive ventilation during exercise training for people with chronic obstructive pulmonary disease (2014) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Outcomes · patients with chronic obstructive pulmonary disease Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease (2014) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Outcomes · patients with chronic obstructive pulmonary disease Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease (2014) · Cochrane | no estimate extracted | NR | No studies |
Comparison of water‐based exercise vs control Quality of life · adults with asthma Water‐based exercise for adults with asthma (2014) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Health‐related quality of life · participants with asthma Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids · participants with asthma Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Health‐related quality of life · participants with exercise‐induced asthma Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids · participants with exercise‐induced asthma Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse events · participants with exercise‐induced asthma Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane | no estimate extracted | NR | No studies |
Inactivated influenza vaccine vs placebo Protection from experiencing an asthma exacerbation of any cause over the influenza season ‐ adults given inactivated influenza vaccine · children and adults with asthma Vaccines for preventing influenza in people with asthma (2013) · Cochrane | no estimate extracted | NR | No studies |
Inactivated influenza vaccine vs placebo Protection from experiencing an influenza‐related asthma exacerbation over the influenza season ‐ adults given inactivated influenza vaccine · children and adults with asthma Vaccines for preventing influenza in people with asthma (2013) · Cochrane | no estimate extracted | NR | No studies |
Inspiratory muscle training vs control Exacerbations requiring a course of oral or inhaled corticosteroids or emergency department visits · Participants with asthma Inspiratory muscle training for asthma (2013) · Cochrane | no estimate extracted | NR | No studies |
SiT for maintenance/relief vs higher‐dose ICS/LABA + SABA Outcomes · Studies recruited adults and adolescents aged 12 and older with chronic asthma Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler… (2013) · Cochrane | no estimate extracted | NR | No studies |
SiT for maintenance/relief vs higher‐dose ICS/LABA + SABA People with exacerbations requiring hospitalisation · Studies recruited adults and adolescents aged 12 and older with chronic asthma Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler… (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life · Participants with primary dysfunctional breathing/hyperventilation syndrome Breathing exercises for dysfunctional breathing/hyperventilation syndrome in adults (2013) · Cochrane | no estimate extracted | NR | No studies |
Nurse‐led vs physician‐led care Frequency of exacerbations · the management of asthma Nurse versus physician‐led care for the management of asthma (2013) · Cochrane | no estimate extracted | NR | No studies |
Nurse‐led vs physician‐led care Asthma severity and symptoms · the management of asthma Nurse versus physician‐led care for the management of asthma (2013) · Cochrane | no estimate extracted | NR | No studies |
Nurse‐led vs physician‐led care Healthcare costs, direct and indirect · the management of asthma Nurse versus physician‐led care for the management of asthma (2013) · Cochrane | no estimate extracted | NR | No studies |
Inhaled corticosteroids (ICS) vs placebo Primary outcome · adults with subacute and chronic cough Inhaled corticosteroids for subacute and chronic cough in adults (2013) · Cochrane | no estimate extracted | NR | No studies |
Inhaled corticosteroids (ICS) vs placebo Secondary outcomes · adults with subacute and chronic cough Inhaled corticosteroids for subacute and chronic cough in adults (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Exacerbations requiring hospital admission · children and adolescents aged 18 years and under studies with asthma Swimming training for asthma in children and adolescents aged 18 years and under (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Exacerbations requiring a course of oral corticosteroids · children and adolescents aged 18 years and under studies with asthma Swimming training for asthma in children and adolescents aged 18 years and under (2013) · Cochrane | no estimate extracted | NR | No studies |
Long‐acting beta2‐agonists vs placebo Outcomes · people with chronic obstructive pulmonary disease Long‐acting beta₂‐agonists for chronic obstructive pulmonary disease (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life · children with dysfunctional breathing/hyperventilation syndrome Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Nijmegen questionnaire · children with dysfunctional breathing/hyperventilation syndrome Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Ventilation · children with dysfunctional breathing/hyperventilation syndrome Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Exercise capacity · children with dysfunctional breathing/hyperventilation syndrome Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dysfunctional breathing‐specific tests (e.g. breath hold test or hyperventilation provocation test (HVPT)) · children with dysfunctional breathing/hyperventilation syndrome Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children (2013) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Vitamin C supplementation vs placebo Adverse events · adults and children with exercise‐induced bronchoconstriction/asthma Vitamin C for asthma and exercise‐induced bronchoconstriction (2013) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Vitamin C supplementation vs placebo Health‐related quality of life (HRQL) · adults and children with exercise‐induced bronchoconstriction/asthma Vitamin C for asthma and exercise‐induced bronchoconstriction (2013) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Vitamin C supplementation vs placebo Asthma exacerbations · adults and children with exercise‐induced bronchoconstriction/asthma Vitamin C for asthma and exercise‐induced bronchoconstriction (2013) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR SAEs ‐ formoterol versus salbutamol · patients with chronic asthma (children) Regular treatment with formoterol for chronic asthma: serious adverse events (2012) · Cochrane | no estimate extracted | NR | No studies |