Cochrane · systematic review · CD000364

Vaccines for preventing influenza in people with asthma

Cates, CJ, Rowe, BH · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 66.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Inactivated influenza vaccine versus placebo

Population: children and adults with asthma
6 questions
OutcomeEffectEvidenceStatus / GRADE
Protection from experiencing an asthma exacerbation of any cause over the influenza season ‐ children (over 6 years of age) given inactivated influenza vaccine
Inactivated influenza vaccine vs placebo
no estimate extracted1 study · 696 participantsModerate
Downgraded: imprecision
Protection from experiencing an influenza‐related asthma exacerbation over the influenza season ‐ children (over 6 years of age) given inactivated influenza vaccine
Inactivated influenza vaccine vs placebo
no estimate extracted1 study · 696 participantsModerate
Downgraded: imprecision
Asthma exacerbation (adverse effects) caused by inactivated influenza vaccine, measured in the first 2 weeks following vaccination ‐ children (over 3 years of age) given inactivated influenza vaccine
Inactivated influenza vaccine vs placebo
no estimate extracted1 study · 712 participantsModerate
Downgraded: imprecision
Protection from experiencing an asthma exacerbation of any cause over the influenza season ‐ adults given inactivated influenza vaccine
Inactivated influenza vaccine vs placebo
no estimate extractedNRNo studies
Protection from experiencing an influenza‐related asthma exacerbation over the influenza season ‐ adults given inactivated influenza vaccine
Inactivated influenza vaccine vs placebo
no estimate extractedNRNo studies
Asthma exacerbation (adverse effects) caused by inactivated influenza vaccine, measured in the first 2 weeks following vaccination ‐ adults given inactivated influenza vaccine
Inactivated influenza vaccine vs placebo
no estimate extracted2 studies · 1526 participantsModerate
Downgraded: risk of bias, imprecision