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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Secondary objectives for HINTS subcomponents
Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular… (2023) · Cochrane
no estimate extractedNRNo studies
Topical ophthalmic anesthetic plus NSAID vs placebo
Changes in mean participant‐reported ocular pain from baseline to 48 hours · corneal abrasion (post‐surgical)
Topical ophthalmic anesthetics for corneal abrasions (2023) · Cochrane
no estimate extractedNRNo studies
Topical ophthalmic anesthetic plus NSAID vs placebo
Changes in mean participant‐reported ocular pain from baseline to 72 hours · corneal abrasion (post‐surgical)
Topical ophthalmic anesthetics for corneal abrasions (2023) · Cochrane
no estimate extractedNRNo studies
Anticoagulant vs different dose of the same anticoagulant
Deep vein thrombosis · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
no estimate extractedNRNo studies
Anticoagulant vs different dose of the same anticoagulant
Pulmonary embolism · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
no estimate extractedNRNo studies
Anticoagulant vs antiplatelet agent
Deep vein thrombosis · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
no estimate extractedNRNo studies
Anticoagulant vs antiplatelet agent
Pulmonary embolism · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
no estimate extractedNRNo studies
Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)
Neurodevelopmental impairment · preterm infants receiving nasal CPAP
Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants (2023) · Cochrane
no estimate extractedNRNo studies
RBD‐specific polyclonal F(ab') 2 fragments of equine antibodies (EpAbs) vs saline placebo
Quality of life · individuals with moderate or severe COVID‐19
Hyperimmune immunoglobulin for people with COVID‐19 (2023) · Cochrane
no estimate extractedNRNo studies
Hyperimmune immunoglobulin from human plasma vs saline placebo
Quality of life · individuals with moderate or severe COVID‐19
Hyperimmune immunoglobulin for people with COVID‐19 (2023) · Cochrane
no estimate extractedNRNo studies
NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention
Pain score assessed up to 10 minutes after the procedure · Procedural pain in neonates
Non‐opioid analgesics for procedural pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention
Episodes of bradycardia, defined as a fall in heart rate of more than 30% below the baseline or less than 100 beats per minute for 10 seconds or longer, occurring during the procedure · Procedural pain in neonates
Non‐opioid analgesics for procedural pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention
Episodes of apnea (mean rates of apnea), occurring during the procedure · Procedural pain in neonates
Non‐opioid analgesics for procedural pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention
Hypotension requiring medical therapy (vasopressors or fluid boluses), occurring during the procedure · Procedural pain in neonates
Non‐opioid analgesics for procedural pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pain score assessed up to 10 minutes after the procedure · Procedural pain in neonates
Non‐opioid analgesics for procedural pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Episodes of bradycardia, defined as a fall in heart rate of more than 30% below the baseline or less than 100 beats per minute for 10 seconds or longer, occurring during the procedure · Procedural pain in neonates
Non‐opioid analgesics for procedural pain in neonates (2023) · Cochrane
no estimate extractedNRNo studies
Beta‐blockers vs placebo
Improvement in vertigo · people with vestibular migraine
Pharmacological interventions for prophylaxis of vestibular migraine (2023) · Cochrane
no estimate extractedNRNo studies
Calcium channel blockers vs no intervention
Serious adverse events · people with vestibular migraine
Pharmacological interventions for prophylaxis of vestibular migraine (2023) · Cochrane
no estimate extractedNRNo studies
SSRIs and SNRIs vs placebo or no treatment
Improvement in vertigo at 6 to ≤ 12 months · adults with PPPD
Pharmacological interventions for persistent postural‐perceptual dizziness (PPPD) (2023) · Cochrane
no estimate extractedNRNo studies
SSRIs and SNRIs vs placebo or no treatment
Change in vertigo at 6 to ≤ 12 months · adults with PPPD
Pharmacological interventions for persistent postural‐perceptual dizziness (PPPD) (2023) · Cochrane
no estimate extractedNRNo studies
SSRIs and SNRIs vs placebo or no treatment
Serious adverse events · adults with PPPD
Pharmacological interventions for persistent postural‐perceptual dizziness (PPPD) (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class I vs Normal Weight or Non‐Obese
OutcomesTime frame of absolute effects · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class II vs Normal Weight or Non‐Obese
Severe COVID · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class II vs Normal Weight or Non‐Obese
Pneumonia · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class II vs Normal Weight or Non‐Obese
 · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class III vs Normal BMI, Non‐obese, or BMI < 40
OutcomesTime frame of absolute effects · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class III vs Normal BMI, Non‐obese, or BMI < 40
Severe COVID · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class III vs Normal BMI, Non‐obese, or BMI < 40
.Pneumonia · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class III vs Normal BMI, Non‐obese, or BMI < 40
 · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity (Unclassified) vs Normal Weight or Non‐Obese
OutcomesTime frame of absolute effects · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity (Unclassified) vs Normal Weight or Non‐Obese
 · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Every 5 units (kg/m2) increase in BMI vs N/A
OutcomesTime frame of absolute effects · Adults with COVID
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Every 5 units (kg/m2) increase in BMI vs N/A
ICU admission · Adults with COVID
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Every 5 units (kg/m2) increase in BMI vs N/A
Pneumonia · Adults with COVID
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Every 5 units (kg/m2) increase in BMI vs N/A
 · Adults with COVID
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class I vs Normal Weight or Non‐Obese
Pneumonia  · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class I vs Normal Weight or Non‐Obese
 · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class II vs Normal Weight or Non‐Obese
OutcomesTime frame of absolute effects · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Ventilation tubes vs non‐surgical treatment
Disease‐specific quality of life · children aged 6 months to 12 years with OME
Ventilation tubes (grommets) for otitis media with effusion (OME) in children (2023) · Cochrane
no estimate extractedNRNo studies
Ventilation tubes vs non‐surgical treatment
Presence/persistence of OME · children aged 6 months to 12 years with OME
Ventilation tubes (grommets) for otitis media with effusion (OME) in children (2023) · Cochrane
no estimate extractedNRNo studies
Ventilation tubes vs myringotomy
Disease‐specific quality of life · children aged 6 months to 12 years with OME
Ventilation tubes (grommets) for otitis media with effusion (OME) in children (2023) · Cochrane
no estimate extractedNRNo studies
Ventilation tubes vs no treatment
Disease‐specific quality of life · children aged 6 months to 12 years with OME
Ventilation tubes (grommets) for otitis media with effusion (OME) in children (2023) · Cochrane
no estimate extractedNRNo studies
Early ventilation tubes vs watchful waiting (treatment later if required)
Disease‐specific quality of life · children aged 6 months to 12 years with OME
Ventilation tubes (grommets) for otitis media with effusion (OME) in children (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Component · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC)…
Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Component · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC)…
Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Non‐nicotine/placebo EC · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC)…
Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Nortriptyline · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC)…
Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network… (2023) · Cochrane
no estimate extractedNRNo studies
Abundant water intake vs no treatment
Change in vertigo · Ménière’s disease
Lifestyle and dietary interventions for Ménière’s disease (2023) · Cochrane
no estimate extractedNRNo studies
Abundant water intake vs no treatment
Serious adverse events · Ménière’s disease
Lifestyle and dietary interventions for Ménière’s disease (2023) · Cochrane
no estimate extractedNRNo studies
Sleeping in darkness vs no treatment
Change in vertigo · Ménière’s disease
Lifestyle and dietary interventions for Ménière’s disease (2023) · Cochrane
no estimate extractedNRNo studies