Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Population

Intervention or exposure

Comparison

Outcome

Any field or review title

Field or topic

Source

Review versions

91 questions in 20 reviews · Colorectal

current versions

No studies 91 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Question	Effect	Evidence	Status / GRADE
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks only Health‐related quality of life · People with primary ventral or incisional hernia repair Mesh fixation techniques in primary ventral or incisional hernia repair (2021) · Cochrane	no estimate extracted	NR	No studies
Absorbable tacks vs nonabsorbable tacks Early postoperative pain (VAS 0 ‐ 10, 2 weeks) · People needing incisional hernia repair Mesh fixation techniques in primary ventral or incisional hernia repair (2021) · Cochrane	no estimate extracted	NR	No studies
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures Health‐related quality of life · People with primary ventral or incisional hernia repair Mesh fixation techniques in primary ventral or incisional hernia repair (2021) · Cochrane	no estimate extracted	NR	No studies
Nonabsorbable tacks vs nonabsorbable sutures Health‐related quality of life · People with primary ventral or incisional hernia repair Mesh fixation techniques in primary ventral or incisional hernia repair (2021) · Cochrane	no estimate extracted	NR	No studies
Physical activity vs usual care Overall survival (time interval between enrolment in the study and death of the person from any cause) · adults with non‐advanced colorectal cancer treated surgically or with neoadjuvant or adjuvant therapy, or both Physical activity interventions for disease‐related physical and mental health during and following… (2020) · Cochrane	no estimate extracted	NR	No studies
Physical activity vs usual care Recurrence‐free survival (time interval between date of enrolment in the study and the date when colorectal cancer recurs or another cancer occurs during the · adults with non‐advanced colorectal cancer treated surgically or with neoadjuvant or adjuvant therapy, or both Physical activity interventions for disease‐related physical and mental health during and following… (2020) · Cochrane	no estimate extracted	NR	No studies
Laparoscopic vs open appendectomy Quality of life · patients with suspected appendicitis Laparoscopic versus open surgery for suspected appendicitis (2018) · Cochrane	no estimate extracted	NR	No studies
Subgroup analysis (publication date) ‐ Laparoscopic vs open appendectomy Pain intensity on day 1 · patients with suspected appendicitis Laparoscopic versus open surgery for suspected appendicitis (2018) · Cochrane	no estimate extracted	NR	No studies
Subgroup analysis (publication date) ‐ Laparoscopic vs open appendectomy Quality of life · patients with suspected appendicitis Laparoscopic versus open surgery for suspected appendicitis (2018) · Cochrane	no estimate extracted	NR	No studies
Virtual reality endoscopy simulation training vs conventional patient‐based training Patient discomfort · health professions trainees in gastrointestinal endoscopy Virtual reality simulation training for health professions trainees in gastrointestinal endoscopy (2018) · Cochrane	no estimate extracted	NR	No studies
Virtual reality endoscopy simulation training vs conventional patient‐based training Composite score of competency · health professions trainees in gastrointestinal endoscopy Virtual reality simulation training for health professions trainees in gastrointestinal endoscopy (2018) · Cochrane	no estimate extracted	NR	No studies
Prosthetic mesh placement vs standard treatment Rehospitalisations/ambulatory visits required for parastomal hernia problems/treatment ( · individuals having a stoma formation Prosthetic mesh placement for the prevention of parastomal herniation (2018) · Cochrane	no estimate extracted	NR	No studies
Mesh vs non‐mesh repair Mortality (within 30 days post‐surgery) · adults undergoing inguinal and femoral hernia repair Mesh versus non‐mesh for inguinal and femoral hernia repair (2018) · Cochrane	no estimate extracted	NR	No studies
Enema plus dexamethasone vs enema alone Postoperative complication(s) · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Air enema vs liquid enema Bowel perforation(s) · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Air enema vs liquid enema Recurrence of intussusception ( · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Air enema vs liquid enema Bowel resection · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Air enema vs liquid enema Postoperative complication(s) · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Enema plus glucagon vs enema alone Bowel perforation(s) · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Enema plus glucagon vs enema alone Recurrent intussusception ( · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Enema plus glucagon vs enema alone Bowel resection · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Enema plus glucagon vs enema alone Postoperative complication(s) · children with intussusception Management for intussusception in children (2017) · Cochrane	no estimate extracted	NR	No studies
Chemotherapy vs best supportive care Progression‐free survival · people with metastatic CRC Second‐line systemic therapy for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Chemotherapy vs best supportive care Overall tumour response · people with metastatic CRC Second‐line systemic therapy for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Quality of life · people with metastatic colorectal cancer ‐ KRAS exon 2 MT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Overall grade 3 to 4 toxicity · people with metastatic colorectal cancer ‐ extended RAS WT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Grade 3 to 4 diarrhoea · people with metastatic colorectal cancer ‐ extended RAS WT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Grade 3 to 4 rash · people with metastatic colorectal cancer ‐ extended RAS WT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Grade 3 to 4 neutropenia · people with metastatic colorectal cancer ‐ extended RAS WT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Quality of life · people with metastatic colorectal cancer ‐ extended RAS WT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Overall grade 3 to 4 toxicity · people with metastatic colorectal cancer ‐ extended RAS MT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Grade 3 to 4 diarrhoea · people with metastatic colorectal cancer ‐ extended RAS MT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Grade 3 to 4 rash · people with metastatic colorectal cancer ‐ extended RAS MT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Grade 3 to 4 neutropenia · people with metastatic colorectal cancer ‐ extended RAS MT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Quality of life · people with metastatic colorectal cancer ‐ extended RAS MT Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Grade 3 to 4 neutropenia · people with metastatic colorectal cancer Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Quality of life · people with metastatic colorectal cancer Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Quality of life · people with metastatic colorectal cancer, not selected by KRAS status Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Quality of life · people with metastatic colorectal cancer, not selected by KRAS status Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Quality of life · people with metastatic colorectal cancer Epidermal growth factor receptor (EGFR) inhibitors for metastatic colorectal cancer (2017) · Cochrane	no estimate extracted	NR	No studies
Chromoscopy vs conventional colonoscopy Adverse events · people undergoing colonoscopy for the detection of polyps Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane	no estimate extracted	NR	No studies