Cochrane · systematic review · CD006476

Management for intussusception in children

Gluckman, S, Karpelowsky, J, Webster, AC, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
6
No studies
9
Included studies
NR
No studies 9 · 60%Ungraded 0 · 0%Very low 0 · 0%Low 6 · 40%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Enema plus glucagon versus enema alone

Population: children with intussusception
5 questions
OutcomeEffectEvidenceStatus / GRADE
Successfully reduced intussusception
Enema plus glucagon vs enema alone
RR 1.09 [0.94, 1.26]2 studies · 218 participantsLow
Downgraded: risk of bias
Bowel perforation(s)
Enema plus glucagon vs enema alone
no estimate extractedNRNo studies
Recurrent intussusception (
Enema plus glucagon vs enema alone
no estimate extractedNRNo studies
Bowel resection
Enema plus glucagon vs enema alone
no estimate extractedNRNo studies
Postoperative complication(s)
Enema plus glucagon vs enema alone
no estimate extractedNRNo studies

Enema plus dexamethasone versus enema alone

Population: children with intussusception
5 questions
OutcomeEffectEvidenceStatus / GRADE
Successfully reduced intussusception
Enema plus dexamethasone vs enema alone
RR 1.01 [0.92, 1.1]2 studies · 356 participantsLow
Downgraded: risk of bias
Bowel perforation(s)
Enema plus dexamethasone vs enema alone
RR 2.63 [0.11, 62.66]1 study · 75 participantsLow
Downgraded: risk of bias, imprecision
Recurrent intussusception (
Enema plus dexamethasone vs enema alone
RR 0.14 [0.03, 0.6]2 studies · 299 participantsLow
Downgraded: risk of bias
Bowel resection
Enema plus dexamethasone vs enema alone
RR 0.88 [0.19, 4.06]1 study · 75 participantsLow
Downgraded: risk of bias, imprecision
Postoperative complication(s)
Enema plus dexamethasone vs enema alone
no estimate extractedNRNo studies

Air enema versus liquid enema

Population: children with intussusception
5 questions
OutcomeEffectEvidenceStatus / GRADE
Successfully reduced intussusception
Air enema vs liquid enema
RR 1.28 [1.1, 1.49]2 studies · 199 participantsLow
Downgraded: risk of bias
Bowel perforation(s)
Air enema vs liquid enema
no estimate extractedNRNo studies
Recurrence of intussusception (
Air enema vs liquid enema
no estimate extractedNRNo studies
Bowel resection
Air enema vs liquid enema
no estimate extractedNRNo studies
Postoperative complication(s)
Air enema vs liquid enema
no estimate extractedNRNo studies