Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

601 questions in 75 reviews · Schizophrenia

current versions
No studies 601 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
HEALTHY LIVING STUDY CIRCLE vs AESTHETIC STUDY CIRCLE
Physical health behaviour ‐ not measured · patients with people with serious mental illness
General physical health advice for people with serious mental illness (2014) · Cochrane
no estimate extractedNRNo studies
HEALTHY LIVING STUDY CIRCLE vs AESTHETIC STUDY CIRCLE
Quality of life ‐ not measured · patients with people with serious mental illness
General physical health advice for people with serious mental illness (2014) · Cochrane
no estimate extractedNRNo studies
HEALTHY LIVING STUDY CIRCLE vs AESTHETIC STUDY CIRCLE
Adverse Effects ‐ not reported · patients with people with serious mental illness
General physical health advice for people with serious mental illness (2014) · Cochrane
no estimate extractedNRNo studies
HEALTHY LIVING STUDY CIRCLE vs AESTHETIC STUDY CIRCLE
Economic ‐ not reported · patients with people with serious mental illness
General physical health advice for people with serious mental illness (2014) · Cochrane
no estimate extractedNRNo studies
PHYSICAL HEALTH ADVICE vs STANDARD CARE
Economic ‐ not reported · patients with people with serious mental illness
General physical health advice for people with serious mental illness (2014) · Cochrane
no estimate extractedNRNo studies
HEALTH EDUCATION vs HEALTH EMPOWERMENT EDUCATION
Physical health awareness ‐ not reported · people with serious mental illness
General physical health advice for people with serious mental illness (2014) · Cochrane
no estimate extractedNRNo studies
HEALTH EDUCATION vs HEALTH EMPOWERMENT EDUCATION
Physical health behaviour ‐ not measured · people with serious mental illness
General physical health advice for people with serious mental illness (2014) · Cochrane
no estimate extractedNRNo studies
Horticultural therapy plus standard care vs standard care alone
Clinical global response · patients with schizophrenia
Horticultural therapy for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
Horticultural therapy plus standard care vs standard care alone
General functioning · patients with schizophrenia
Horticultural therapy for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
Horticultural therapy plus standard care vs standard care alone
Physical fitness · patients with schizophrenia
Horticultural therapy for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
Horticultural therapy plus standard care vs standard care alone
Adverse effect · patients with schizophrenia
Horticultural therapy for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
BRIEF FAMILY INTERVENTION vs STANDARD CARE
Service utilisation ‐ days in hospital ‐ medium to long term ‐ not reported · patients with schizophrenia
Family intervention (brief) for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
BRIEF FAMILY INTERVENTION vs STANDARD CARE
Global state ‐ compliance with medication ‐ medium to long term ‐ not reported · patients with schizophrenia
Family intervention (brief) for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
BRIEF FAMILY INTERVENTION vs STANDARD CARE
Quality of life/satisfaction with care ‐ for recipients or carers ‐ medium to long term ‐ not reported · patients with schizophrenia
Family intervention (brief) for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
BRIEF FAMILY INTERVENTION vs STANDARD CARE
Economic outcomes ‐ costs of care ‐ long term ‐ not reported · patients with schizophrenia
Family intervention (brief) for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) FOR PROMPTING/SUPPORT + STANDARD CARE vs STANDARD CARE
Service utilisation ‐ not reported · patients with treatment compliance for people with serious mental illness
Information and communication technology based prompting for treatment compliance for people with serious… (2014) · Cochrane
no estimate extractedNRNo studies
User‐held information vs standard information
Death: causes other than suicide ‐ not reported · patients with routine care of people with severe mental illness
User‐held personalised information for routine care of people with severe mental illness (2013) · Cochrane
no estimate extractedNRNo studies
User‐held information vs standard information
Violence ‐ not reported · patients with routine care of people with severe mental illness
User‐held personalised information for routine care of people with severe mental illness (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE vs ANY ANTIPSYCHOTIC
Quality of life: no significant change in quality of life/satisfaction medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANY ANTIPSYCHOTIC
Mental state: no improvementmedium term (3‐12 months)not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANY ANTIPSYCHOTIC
Mental state: presence of first‐rank symptoms medium term (3‐12 months)not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANY ANTIPSYCHOTIC
Adverse effects: extrapyramidal adverse effects Parkinsonismshort term (< 3 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANY ANTIPSYCHOTIC
Adverse effects: extrapyramidal adverse effects Parkinsonismmedium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE vs PLACEBO
Mental state: no improvement medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANTIPSYCHOTIC + PLACEBO
Mental state: no improvement medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANTIPSYCHOTIC + PLACEBO
Mental state: presence of first‐rank symptoms medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANTIPSYCHOTIC + PLACEBO
Adverse effects: extrapyramidal adverse effects Parkinsonism short term (< 3 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANTIPSYCHOTIC + ANTIPSYCHOTIC
Global state: relapse medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANTIPSYCHOTIC + ANTIPSYCHOTIC
Mental state: no improvement medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANTIPSYCHOTIC + ANTIPSYCHOTIC
Mental state: presence of first‐rank symptoms medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE vs PLACEBO
Mental state: specific symptoms first‐rank symptoms medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE + ANY ANTIPSYCHOTIC vs ANTIPSYCHOTIC + ANTIPSYCHOTIC
Quality of life: average change score medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
PIMOZIDE vs PLACEBO
Quality of life: no significant change in quality of life/satisfaction medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses
Pimozide for schizophrenia or related psychoses (2013) · Cochrane
no estimate extractedNRNo studies
DANCE THERAPY vs STANDARD CARE
Service utilisation‐days in hospital · patients with schizophrenia
Dance therapy for schizophrenia (2013) · Cochrane
no estimate extractedNRNo studies
NIDOTHERAPY‐ENHANCED STANDARD CARE vs STANDARD CARE
Functioning ‐ general ‐ no important change ‐ medium term (6‐12 months) ‐ not measured · patients with people with schizophrenia
Nidotherapy for people with schizophrenia (2013) · Cochrane
no estimate extractedNRNo studies
NIDOTHERAPY‐ENHANCED STANDARD CARE vs STANDARD CARE
Quality of life ‐ no important change ‐ medium term (6‐12 months) ‐ not measured · patients with people with schizophrenia
Nidotherapy for people with schizophrenia (2013) · Cochrane
no estimate extractedNRNo studies
ADJUNCTIVE TREATMENT ‐ NON‐SPECIFIC: SELEGILINE vs PLACEBO
Quality of life Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
ADJUNCTIVE TREATMENT ‐ NON‐SPECIFIC: SELEGILINE vs PLACEBO
Adverse effects: Death Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE vs MAINTENANCE RISPERIDONE
Quality of life Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE vs MAINTENANCE RISPERIDONE
Adverse effects: Death Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE vs MAINTENANCE RISPERIDONE
Adverse effects: Extrapyramidal symptoms Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE vs MAINTENANCE RISPERIDONE/FGA
Quality of life Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE vs MAINTENANCE RISPERIDONE/FGA
Adverse effects: Death Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL vs PLACEBO
Quality of life Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL vs PLACEBO
Adverse effects: Death Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL vs PLACEBO
Adverse effects: Psychotic symptoms Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL vs PLACEBO
Adverse effects: Extrapyramidal symptoms Not reported · patients with sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane
no estimate extractedNRNo studies
BENZODIAZEPINES AS SOLE TREATMENT vs PLACEBO
Number of participants tranquillised at endpoint of the study (Desired sedation/tranquillisation) · people with schizophrenia
Benzodiazepines for schizophrenia (2012) · Cochrane
no estimate extractedNRNo studies
Paliperidone palmitate vs risperidone long‐acting injection
Cost ‐ not measured · patients with schizophrenia
Paliperidone palmitate for schizophrenia (2012) · Cochrane
no estimate extractedNRNo studies
Paliperidone palmitate vs risperidone long‐acting injection
Health related quality of life ‐ not measured · patients with schizophrenia
Paliperidone palmitate for schizophrenia (2012) · Cochrane
no estimate extractedNRNo studies