What do systematic reviews say?

Serious adverse events ‐ not reported · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19

Adverse events considered non‐serious · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

Serious adverse events ‐ not reported · women with recurrent or FIGO stage IVB cervical cancer

Adverse events/serious adverse events · people with NMD

Adverse events/serious adverse events · people with NMD

Adverse events/serious adverse events · people with NMD

Proportion of children adverse events · children with nocturnal enuresis

Adverse events (maternal or neonatal) · women undergoing caesarean section

Adverse events (maternal or neonatal) · women undergoing caesarean section

Adverse events (timing not specified) · people undergoing major amputation of the lower extremity

Serious adverse events ‐ not reported · participants with quiescent IBD

Serious adverse events ‐ not reported · participants with quiescent IBD

Serious adverse events ‐ not reported · children with bronchiectasis

Serious adverse events ‐ not reported · adults with bronchiectasis

Serious adverse events ‐ not reported · post‐prostatectomy erectile dysfunction (long‐term)

Serious adverse events ‐ not reported · post‐prostatectomy erectile dysfunction (short‐term)

Serious adverse events ‐ not reported · post‐prostatectomy erectile dysfunction (long‐term)

Serious adverse events – not reported · people with a low platelet count

Risk of adverse events ‐ not reported · participants at risk of high altitude illness

Risk of adverse events ‐ not reported · participants at risk of high altitude illness