Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

316 questions · 321 findings · 136 reviews

No studies found 52 · 16.2%GRADE not reported 21 · 6.5%Very low 115 · 35.8%Low 92 · 28.7%Moderate 33 · 10.3%High 8 · 2.5%

All doses of cerivastatin vs placebo

Withdrawals due to adverse events · participants with normal or abnormal lipid profiles

It is very uncertain whether all doses of cerivastatin changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Adalimumab vs placebo

Withdrawals due to adverse events · Participants with Crohn's disease in remission

Adalimumab probably leads to lower withdrawals due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Anti‐TNF discontinuation vs anti‐TNF continuation

Withdrawals due to adverse events · people with rheumatoid arthritis with low disease activity using a standard dose of anti‐TNF agents

Anti‐TNF discontinuation showed no clear difference in withdrawals due to adverse events compared with anti‐TNF continuation (moderate certainty).

1 finding from 1 review

Anti‐TNF dose reduction vs anti‐TNF continuation

Withdrawals due to adverse events · people with rheumatoid arthritis with low disease activity using a standard dose of anti‐TNF agents

Anti‐TNF dose reduction showed no clear difference in withdrawals due to adverse events compared with anti‐TNF continuation (low certainty).

1 finding from 1 review

Intervention not reported

Withdrawals due to adverse events · Patients with active Crohn's disease

The intervention showed no clear difference in withdrawals due to adverse events (low certainty).

1 finding from 1 review

Acupuncture vs NSAIDs

Withdrawals due to adverse events · patients with hip osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture vs sham

Withdrawals due to adverse events · patients with hip osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Mesalamine vs placebo

Withdrawals due to adverse events · Patients with collagenous colitis

Mesalamine showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Budesonide vs placebo

Withdrawals due to adverse events · Patients with collagenous colitis

It is very uncertain whether budesonide changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Boswellia serrata vs placebo

Withdrawals due to adverse events · Patients with collagenous colitis

Boswellia serrata extract showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review