Findings

What do systematic reviews say?

269 questions · 282 findings · 133 reviews

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No studies found 40 · 14.2%GRADE not reported 69 · 24.5%Very low 60 · 21.3%Low 69 · 24.5%Moderate 37 · 13.1%High 7 · 2.5%

Summary of findings (water exercise vs no exercise

Quality of life St George's Respiratory Questionnaire (SGRQ) score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Water‐based exercise training for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
no estimate extracted
19 participants
Low

Primary‐level worker‐led collaborative care vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with common mental disorders

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2199 participants
Low

Low‐intensity pulsed ultrasound vs control

QoL · acute fractures in adults; included studies assessed effects in complete upper limb fractures (distal radius, clavicle, scaphoid,…

1 finding from 1 review

Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 393 participants
Very low

Summary of findings (water exercise vs land exercise)

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Water‐based exercise training for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
no estimate extracted
60 participants
Low

Intervention not reported

HrQoL and self esteem a. DUX 25 (Dutch Child AZL TNO Quality‐of‐Life tool: total score and 4 domains; scale 0 to 100; higher score indicates better HrQoL) · preschool children (aged 0 to 6 years) with overweight or obesity

1 finding from 1 review

Diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool… 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Intervention not reported

Self‐perceived QoL (change from baseline) measured using Peds QL 4.0 Generic Core Scales, scoring 0‐100 points, higher score indicates better quality of life) · children with chronic constipation

1 finding from 1 review

Transcutaneous electrical stimulation (TES) for treatment of constipation in children 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Intervention not reported

Parent‐perceived QoL (change from baseline) measured using PedsQL 4.0 Generic Core Scales, scoring 0‐100 points, higher score indicates better quality of life) · children with chronic constipation

1 finding from 1 review

Transcutaneous electrical stimulation (TES) for treatment of constipation in children 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Exercise vs usual care

Health‐related quality of lifeg Median · people with ESKD

Exercise may leads to higher HRQoL Investigators measured health related quality of life using… compared with usual care (low certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
MD 3.06 [2.29, 3.83]
2 studies · 64 participants
Low

Intervention not reported

HRQoL using EQ‐ 5D (range 0 to 1), SF‐36 (range 0 to 100), SF‐12 (range 0 to 100), and WHOQOL‐BREF (range 0 to 130). A higher score indicates better quality of life. · adults following hip fracture surgery

The intervention showed no clear difference in HRQoL using EQ‐ 5D (range 0 to 1), SF‐36 (range 0 to 100), SF‐12… (moderate certainty).

1 finding from 1 review

Interventions for improving mobility after hip fracture surgery in adults 2022 · Cochrane Headline outcomes only
SMD 0.14 [0, 0.29]
10 studies · 785 participants
Moderate

Patisiran vs placebo

QoL · people with TTR‐FAP

1 finding from 1 review

Pharmacological treatment for familial amyloid polyneuropathy 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 225 participants
Low

Inotersen vs placebo

QoL · people with TTR‐FAP

1 finding from 1 review

Pharmacological treatment for familial amyloid polyneuropathy 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 172 participants
Low

Tafamidis vs placebo

QoL · people with early‐stage TTR‐FAP

1 finding from 1 review

Pharmacological treatment for familial amyloid polyneuropathy 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 125 participants
Very low

Intervention not reported

Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Intervention not reported

Health‐related quality of life (health status) COPD Assessment Tool. Scale from 0 to 5; higher score indicates worse HRQoL Contains 10 questions with 5‐point Likert scale · individuals with stable bronchiectasis

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low

Group 1 Pulmonary arterial hypertension ‐ PDE5i vs placebo

QoL · pulmonary arterial hypertension

1 finding from 1 review

Phosphodiesterase 5 inhibitors for pulmonary hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 163 participants
GRADE not reported

Mechanically assisted walking training with body weight support vs no walking training

Quality of life Measured by: PedsQOL‐CP score (range from 0 to 100; higher scores = better quality of life) Timing of outcome assessment: change scores from baseline to 12 weeks · children with cerebral palsy classified within GMFCS Levels I to V and between 3 and 18 years of age

1 finding from 1 review

Mechanically assisted walking training for walking, participation, and quality of life in children with cerebral palsy 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Low

Anti‐VEGF vs sham

QoL · macular oedema secondary to branch retinal vein occlusion

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 281 participants
Moderate

SCS treatment for 7 or fewer days vs SCS treatment

QoL · exacerbations of COPD

1 finding from 1 review

Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 271 participants
Moderate

Intervention not reported

Health‐related quality of life (HRQOL), SD units: measured on FACIT‐Pal, TOI of FACT‐Hep, TOI of FACT‐L, FACT‐G, McGill Quality of Life, FACIT‐Sp. Higher scores indicate better HRQOL. · patients with advanced cancer

1 finding from 1 review

Early palliative care for adults with advanced cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1028 participants
Low

Intervention not reported

Health‐related quality of life (cough‐specific) Leicester Cough Questionnaire Scale from 0 to 133; higher score indicates better HRQoL. Contains 19 questions from 3 domains on a Likert scale · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low