Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

81 questions · 81 findings · 45 reviews

No studies found 17 · 21%GRADE not reported 4 · 4.9%Very low 44 · 54.3%Low 10 · 12.3%Moderate 4 · 4.9%High 2 · 2.5%

Bioengineered devices vs standard techniques

Adverse events assessed as: adverse events (serious and non‐serious) · people undergoing peripheral nerve repair of the upper limb

It is very uncertain whether bioengineered devices changes adverse events assessed as: adverse events (serious and non‐serious) compared with standard techniques (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Adverse events considered non‐serious (penicillin versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus doxycycline) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Non‐serious adverse events Maximum · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Intervention not reported

Non‐serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)

The intervention showed no clear difference in non‐serious adverse eventsClinical manifestation and laboratory… (low certainty).

1 finding from 1 review

Methylphenidate vs placebo or no intervention

Adverse events considered non‐serious (penicillin versus doxycycline) · Children and adolescents with ADHD

It is very uncertain whether methylphenidate changes proportion of participants with one or more adverse events… compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Intervention not reported

Non‐serious local adverse events (low risk of bias) inactivated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.

The intervention showed no clear difference in non‐serious local adverse events (low risk of bias) inactivated HAV… (high certainty).

1 finding from 1 review

Intervention not reported

Non‐serious systemic adverse events (low risk of bias) inactivated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.

The intervention showed no clear difference in non‐serious systemic adverse events (low risk of bias) inactivated… (high certainty).

1 finding from 1 review

Intervention not reported

Non‐serious local adverse events (low risk of bias) live attenuated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Non‐serious systemic adverse events (all included studies) inactivated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.

The intervention showed no clear difference in non‐serious systemic adverse events (all included studies)… (low certainty).

1 finding from 1 review

Intervention not reported

Non‐serious systemic adverse events (low risk of bias) live attenuated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Non‐serious local adverse events (all included studies) live attenuated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Non‐serious systemic adverse events (all included studies) live attenuated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Non‐serious adverse events for all placebos compared with wait‐list or no treatment (Spontaneous reporting of dichotomous outcomes) (Post‐treatment) · patients with mental health disorders

It is very uncertain whether the intervention changes non‐serious adverse events for all placebos compared with wait‐list… (very low certainty).

1 finding from 1 review