Findings

What do systematic reviews say?

688 questions · 708 findings · 336 reviews

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No studies found 374 · 52.8%GRADE not reported 21 · 3%Very low 110 · 15.5%Low 118 · 16.7%Moderate 62 · 8.8%High 23 · 3.2%

Intervention not reported

Health‐related quality of life (HRQOL), natural units: measured on FACT‐G (from 0 to 108) · patients with advanced cancer

1 finding from 1 review

Early palliative care for adults with advanced cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1028 participants
Low

Intervention not reported

Knee‐specific health‐related quality of lifea Scale: 0 to 100, 100 is best quality of life · people with degenerative knee disease (osteoarthritis including degenerative meniscal tears)

1 finding from 1 review

Arthroscopic surgery for degenerative knee disease (osteoarthritis including degenerative meniscal tears) 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 188 participants
Moderate

Anti‐IL‐4Rα mAb (dupilumab) vs placebo (on top of topical steroids)

Disease‐specific quality of life · patients with severe chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 784 participants
High

Anti‐IgE mAb (omalizumab) vs placebo (on top of topical steroids)

Disease‐specific quality of life · patients with chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 265 participants
Moderate

Anti‐IL‐5 mAb (mepolizumab) vs placebo (on top of topical steroids)

Disease‐specific quality of life · patients with severe chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 105 participants
Low

Diaphragmatic breathing vs no breathing exercises

Health‐related quality of life Change in total score of St George Respiratory Questionnaire · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Moderate

Physical exercise training vs no exercise

Physical functioning component of health‐related quality of life, measured using various scales · adults with advanced lung cancer

1 finding from 1 review

Exercise training for advanced lung cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 73 participants
Low

Summary of findings table ‐ Rifaximin vs non‐absorbable disaccharide

Health‐related quality of life ‐ all trials Higher scores indicate improved health‐related quality of life · prevention and treatment of hepatic encephalopathy in people with cirrhosis

1 finding from 1 review

Rifaximin for prevention and treatment of hepatic encephalopathy in people with cirrhosis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 249 participants
Very low

Summary of findings table ‐ Rifaximin vs placebo or no intervention

Health‐related quality of life ‐ all trials Higher scores indicate improved health‐related quality of life · prevention and treatment of hepatic encephalopathy in people with cirrhosis

1 finding from 1 review

Rifaximin for prevention and treatment of hepatic encephalopathy in people with cirrhosis 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 214 participants
Moderate

Palliative care vs usual care

Health‐related quality of life Assessed by: SeiQoL‐DW (higher scores mean better quality of life) · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…

1 finding from 1 review

Palliative care interventions for people with multiple sclerosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low

Exercise vs no exercise

Health‐related quality of life (HRQoL) · people with Child‐Pugh stage A or B cirrhosis

1 finding from 1 review

Physical exercise for people with cirrhosis 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 81 participants
Low

Spinal cord stimulation vs placebo

QoL · adults with low back pain

1 finding from 1 review

Spinal cord stimulation for low back pain 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Moderate

Pulmonary rehabilitation vs usual care

Health‐related quality of life Change in total score of St George Respiratory Questionnaire · post‐exacerbation COPD

1 finding from 1 review

Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1003 participants
High

Summary of findings ‐ Inhaled mannitol vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · people with bronchiectasis

Inhaled mannitol showed no clear difference in health‐related quality of life measured on the SGRQ Scale from 0 to… compared with placebo (moderate certainty).

1 finding from 1 review

Inhaled hyperosmolar agents for bronchiectasis 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 840 participants
Moderate

Neurodynamic mobilisation vs no treatment

Long‐term improvement in functional ability or health‐related quality of life (more than three months) · People with carpal tunnel syndrome on a waiting list for carpal tunnel release

1 finding from 1 review

Exercise and mobilisation interventions for carpal tunnel syndrome 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Telemedicine vs usual care

HRQoL: using EQ‐5D (range from 0 to 1; higher values indicate better quality of life

1 finding from 1 review

Interventions for people with type 2 diabetes mellitus fasting during Ramadan 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 85 participants
Very low

Anti‐IL‐4Rα mAb (dupilumab) vs placebo (on top of topical steroids)

Generic quality of life measures · patients with severe chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 766 participants
Moderate

Hospital‐based specialist palliative care vs usual care

Health‐related quality of life (HRQoL) · adults with advanced illness and their unpaid caregivers/families

1 finding from 1 review

The effectiveness and cost‐effectiveness of hospital‐based specialist palliative care for adults with advanced illness… 2020 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1344 participants
Low

Intervention not reported

Health‐related quality of life ‐ PCS physical component summary ‐ MCS mental component summary at maximum · adults with compensated or decompensated advanced chronic liver disease

1 finding from 1 review

Granulocyte colony‐stimulating factor with or without stem or progenitor cell or growth factors infusion for people… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 165 participants
Very low

Surgery vs splint

Health‐related quality of life (EQ‐5D) ‐ Long‐term improvement: > 3 months Scale: 0 to 1, higher is better · carpal tunnel syndrome

1 finding from 1 review

Surgical versus non‐surgical treatment for carpal tunnel syndrome 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 167 participants
Low