Cochrane · systematic review · CD012678

Physical exercise for people with cirrhosis

Aamann, L, Dam, G, Rinnov, AR, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Exercise compared to no exercise for people with cirrhosis

Population: people with Child‐Pugh stage A or B cirrhosis
7 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality
Exercise vs no exercise
RR 0.19 [0.01, 3.73]6 studies · 173 participantsModerate
Downgraded: imprecision
Serious adverse events
Exercise vs no exercise
RR 0.61 [0.19, 1.94]6 studies · 173 participantsLow
Downgraded: risk of bias, imprecision
Health‐related quality of life ‐ CLDQ (total score 1–7, high score corresponds to a better HRQoL)
Exercise vs no exercise
no estimate extracted3 studies · 81 participantsLow
Downgraded: risk of bias, imprecision
Anthropometric measurements: mid‐arm circumference (cm)
Exercise vs no exercise
no estimate extracted3 studies · 72 participantsLow
Downgraded: risk of bias, imprecision
Anthropometric measurements: mid‐thigh circumference (cm)
Exercise vs no exercise
no estimate extracted5 studies · 128 participantsLow
Downgraded: risk of bias, imprecision
Physical fitness: peak exercise oxygen uptake (mL/kg/minute)
Exercise vs no exercise
no estimate extracted4 studies · 100 participantsLow
Downgraded: risk of bias, imprecision
Physical fitness: 6‐Minute Walk Test (min in total)
Exercise vs no exercise
no estimate extracted4 studies · 105 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency