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Evidence found and GRADE certainty

28 questions · 28 findings · 15 reviews

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No studies found 5 · 17.9%GRADE not reported 12 · 42.9%Very low 6 · 21.4%Low 2 · 7.1%Moderate 3 · 10.7%High 0 · 0%

CHLORPROMAZINE vs piperacetazine

Global state: clinically important change in global state · patients with schizophrenia

It is very uncertain whether chlorpromazine changes global state: clinically important change ‐ as defined by each of… compared with piperacetazine (very low certainty).

1 finding from 1 review

α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL

Global state: clinically important change in global state needing additional medication ‐ chlorpromazine · patients with schizophrenia

It is very uncertain whether α‐FLUPENTHIXOL changes global state: clinically important change in global state needing… compared with PLACEBO or β‐FLUPENTHIXOL (very low certainty).

1 finding from 1 review

WENDAN DECOCTION vs placebo or no treatment

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION may leads to lower global state: Clinically important change ‐ no improvement ‐ defined… compared with PLACEBO OR NO TREATMENT (low certainty).

1 finding from 1 review

WENDAN DECOCTION PLUS NORMAL DOSE ANTIPSYCHOTIC vs STANDARD DOSE ANTIPSYCHOTICS

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION PLUS NORMAL DOSE ANTIPSYCHOTIC probably leads to lower global state: Clinically important change ‐ no improvement ‐ defined… compared with NORMAL DOSE ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC vs STANDARD DOSE ANTIPSYCHOTICS

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC probably leads to lower global state: Clinically important change ‐ no improvement ‐ defined… compared with NORMAL DOSE ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION vs antipsychotics

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION showed no clear difference in global state: Clinically important change ‐ no improvement ‐ defined… compared with ANTIPSYCHOTIC DRUG (moderate certainty).

1 finding from 1 review

Magnetic seizure therapy plus standard care vs electroconvulsive therapy plus standard care

Global state: clinically important change in global state · people with the acute phase of schizophrenia

It is very uncertain whether magnetic seizure therapy plus standard care changes global state: clinically important change assessed by: number of… compared with electroconvulsive therapy plus standard care (very low certainty).

1 finding from 1 review