Cochrane · systematic review · CD006570
Benzodiazepines for catatonia in people with schizophrenia or other serious mental illnesses
Zaman, H, Gibson, RC, Walcott, G · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
1
No studies
6
Included studies
NR
No studies 6 · 85.7%Ungraded 0 · 0%Very low 1 · 14.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Lorazepam compared to Oxazepam for catatonia in people with schizophrenia or other SMI
Population: catatonia in people with schizophrenia or SMI
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Catatonia: clinically important change in catatonia symptoms (improved at least 50% on the VAS) Lorazepam vs Oxazepam | RR 0.95 [0.42, 2.16] | 1 study · 17 participants | Very low Downgraded: risk of bias |
Service use: duration of stay in hospital Lorazepam vs Oxazepam | no estimate extracted | NR | No studies |
Satisfaction with care: clinically important change in satisfaction by informal care‐givers Lorazepam vs Oxazepam | no estimate extracted | NR | No studies |
Satisfaction with care: clinically important change in satisfaction by recipients of care Lorazepam vs Oxazepam | no estimate extracted | NR | No studies |
Global state: clinically important change in global state (as defined by individual studies) Lorazepam vs Oxazepam | no estimate extracted | NR | No studies |
Adverse effects: incidence of clinically important adverse effect Lorazepam vs Oxazepam | no estimate extracted | NR | No studies |
General functioning: clinically important change in specific aspects of functioning, such as life skills ‒ as defined by each of the studies Lorazepam vs Oxazepam | no estimate extracted | NR | No studies |