Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

89 questions · 96 findings · 36 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 20 · 20.8%GRADE not reported 5 · 5.2%Very low 31 · 32.3%Low 19 · 19.8%Moderate 18 · 18.8%High 3 · 3.1%

iMRI image‐guided surgery vs surgery

Adverse events · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

5‐ALA image‐guided surgery vs surgery

Adverse events · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Neuronavigation image‐guided surgery vs surgery

Adverse events · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Probiotics vs placebo

Adverse events · participants with cancer treated with radiotherapy (with or without chemotherapy)
2 findings from 1 review

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

Adverse events · people with single or solitary brain metastasis

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events compared with stereotactic radiosurgery (very low certainty).

1 finding from 1 review

Adverse events with anti‐gram‐positive antibiotics vs placebo

Any adverse events · people with cancer who have febrile neutropenia

It is very uncertain whether adverse events with anti‐gram‐positive antibiotics changes any adverse events compared with placebo (very low certainty).

1 finding from 1 review