Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

71 questions · 72 findings · 29 reviews · Bone, Joint and Muscle Trauma

No studies found 16 · 22.2%GRADE not reported 9 · 12.5%Very low 37 · 51.4%Low 6 · 8.3%Moderate 3 · 4.2%High 1 · 1.4%

Summary of findings: whole‐body cryotherapy (WBC) vs control (no WBC or passive rest)

Adverse events · physically‐active adults partaking in exercise designed to produce delayed onset muscle soreness (most trial participants were male)

The review found no eligible studies for this question.

1 finding from 1 review

Circular external fixation with limited internal fixation (hybrid fixation) vs standard open reduction internal fixation

Adverse eventse · adults with tibial plateau fracture (Schatzker types V or VI)

It is very uncertain whether circular external fixation with limited internal fixation (hybrid… changes adverse eventse compared with standard open reduction internal fixation (very low certainty).

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Serious adverse events · Children and adolescents with femoral shaft fractures

Surgical interventions may leads to higher serious adverse events compared with conservative interventions (low certainty).

1 finding from 1 review

Summary of findings: Injection therapies vs placebo or no injection control

Adverse events At final · individuals with an investigator‐reported diagnosis of Achilles tendinopathy (or related terminology, e.g. tendinitis). We excluded trials…

It is very uncertain whether summary of findings: Injection therapies changes adverse events At final compared with placebo or no injection control (very low certainty).

1 finding from 1 review