Cochrane · systematic review · CD010960

Injection therapies for Achilles tendinopathy

Kearney, RS, Parsons, N, Metcalfe, D, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Bone, Joint and Muscle TraumaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 57.1%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings: Injection therapies versus placebo or no injection control

Population: individuals with an investigator‐reported diagnosis of Achilles tendinopathy (or related terminology, e.g. tendinitis). We excluded trials focusing on the treatment of individuals with systemic conditions (e.g. rheumatoid arthritis and diabetes)1
7 questions
OutcomeEffectEvidenceStatus / GRADE
VISA‐A (score 0 to 100; 100 = no problems) At 6 weeks
Summary of findings: Injection therapies vs placebo or no injection control
MD 0.795 studies · 200 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
VISA‐A (score 0 to 100; 100 = no problems) At 3 months
Summary of findings: Injection therapies vs placebo or no injection control
no estimate extracted5 studies · 189 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
VISA‐A (score 0 to 100; 100 = no problems) After 3 months (6 to 12 months)
Summary of findings: Injection therapies vs placebo or no injection control
MD 0.143 studies · 132 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Adverse events At final
Summary of findings: Injection therapies vs placebo or no injection control
RR 0.97 [0.5, 1.89]13 studies · 449 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Pain (VAS; score 0 to 100; 0 = no pain)
Summary of findings: Injection therapies vs placebo or no injection control
no estimate extracted7 studies · 219 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Return to sports At final
Summary of findings: Injection therapies vs placebo or no injection control
RR 1.39 [1, 1.94]7 studies · 335 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Patient satisfaction (number of participants satisfied with their treatment) At final
Summary of findings: Injection therapies vs placebo or no injection control
RR 1.05 [0.76, 1.47]4 studies · 152 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness