Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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RotaTeq vs placebo

Serious adverse events: intussusception · children

RotaTeq showed no clear difference in serious adverse events: intussusception compared with placebo (low certainty).

3 findings from 1 review

Steroid therapy in first episode of nephrotic syndrome: five to seven months vs three months

Adverse events: psychological disorders · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: five to… showed no clear difference in adverse events: psychological disorders compared with three months (low certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: psychological disorders · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: psychological disorders compared with 2 months of therapy (low certainty).

1 finding from 1 review

Heparin plus aspirin vs aspirin

Adverse events in the mother ‐ Bleeding · women with persistent antiphospholipid antibodies and recurrent pregnancy loss

Heparin plus aspirin showed no clear difference in adverse events in the mother ‐ Bleeding compared with aspirin (low certainty).

1 finding from 1 review

Aspirin vs placebo

Adverse events in the mother ‐ Bleeding · women with persistent antiphospholipid antibodies and recurrent pregnancy loss

It is very uncertain whether aspirin changes adverse events in the mother ‐ Bleeding compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events during treatment · participants with alcoholic hepatitis at high risk of mortality and morbidity

It is very uncertain whether the intervention changes serious adverse events during treatment (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events Intra‐operative bleeding · participants with β‐thalassaemia

It is very uncertain whether the intervention changes adverse events Intra‐operative bleeding (very low certainty).

1 finding from 1 review