Cochrane · systematic review · CD010517
Splenectomy for people with thalassaemia major or intermedia
Sharma, A, Easow Mathew, M, Puri, L · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Cystic Fibrosis and Genetic DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
3
No studies
6
Included studies
NR
No studies 6 · 66.7%Ungraded 0 · 0%Very low 3 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: participants with β‐thalassaemia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Frequency of transfusion | no estimate extracted | NR | No studies |
Adverse events Post‐operative bleeding | RR 5 [0.26, 95.61] | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events Post‐operative atelectasis | RR 0.5 | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events Intra‐operative bleeding | RR 7 | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life | no estimate extracted | NR | No studies |
Non‐serious adverse events | no estimate extracted | NR | No studies |
Haeatological indices | no estimate extracted | NR | No studies |
Duration of hospital stay | no estimate extracted | NR | No studies |
Serum ferritin | no estimate extracted | NR | No studies |