Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Intervention not reported

Adverse events related to RIPC · patients undergoing a surgical intervention that induces kidney injury

The intervention showed no clear difference in adverse events related to RIPC (high certainty).

1 finding from 1 review

Vortioxetine vs SNRIs

Adverse effects (drop‐outs due to adverse effects4) · adults with Major Depressive Disorder

It is very uncertain whether vortioxetine changes drop‐out due to adverse events compared with SNRIs (very low certainty).

1 finding from 1 review

Vortioxetine vs placebo

Adverse effects (drop‐outs due to adverse effects4) · adults with Major Depressive Disorder

Vortioxetine probably leads to higher drop‐out due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Percutaneous endoscopic gastrostomy vs nasogastric tube feeding

Adverse events irrespective of · adult patients with swallowing disturbances

Percutaneous endoscopic gastrostomy showed no clear difference in adverse events irrespective of compared with nasogastric tube feeding (moderate certainty).

1 finding from 1 review

Intervention not reported

Dropouts due to adverse events · patients with Alzheimer's disease

The intervention showed no clear difference in dropouts due to adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events due to treatment · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…
1 finding from 1 review

Anticoagulant vs different dose of the same anticoagulant

Adverse events (minor bleeding) · non‐hospitalised individuals with COVID‐19 (asymptomatic and mild disease)

Anticoagulant showed no clear difference in adverse events (minor bleeding) compared with different dose of the same anticoagulant (low certainty).

1 finding from 1 review