Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Context-dependent effectiveness of autologous platelet concentrates in regenerative endodontic procedures and periapical surgery: A…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Apicoectomy versus apical curettage in combination with or without L-PRF application: a randomized clinical trial. Gulsever 2025 · Gulsever Serap, Ersahan Seyda, et al. · Scientific reports PMID:40057596 | 2025 | 2 | none stated | not extracted yet |
| Impact of Advanced Platelet-Rich Fibrin on Early Bone Healing After Endodontic Microsurgery: A Randomized Controlled Trial. Karkle 2025 · Karkle Aleksandra, Neimane Laura, et al. · Diagnostics (Basel, Switzerland) PMID:40075764 | 2025 | 2 | 1 | not extracted yet |
| Evaluation of postoperative pain and healing following regenerative endodontics using platelet-rich plasma versus conventional endodontic treatment… Ahmed 2023 · Ahmed Yassmin Elsayed, Ahmed Geraldine Mohamed, et al. · International endodontic journal PMID:36565044 | 2023 | 2 | 1 | not extracted yet |
| Volumetric evaluation of effects of platelet-rich fibrin and concentrated growth factor on early bone healing after endodontic microsurgery: a… You 2023 · You Jae-Seek, Jung Gyeo-Woon, et al. · BMC oral health PMID:37899448 | 2023 | 2 | none stated | not extracted yet |
| Assessment of bone healing after mineral trioxide aggregate and platelet-rich fibrin application in periapical lesions using cone-beam computed… Karan 2020 · Karan Nazife Begüm, Aricioğlu Banu · Clinical oral investigations PMID:31321573 | 2020 | 2 | none stated | not extracted yet |
| Pain and quality of life after endodontic surgery with or without advanced platelet-rich fibrin membrane application: a randomized clinical trial. Soto-Peñaloza 2020 · Soto-Peñaloza David, Peñarrocha-Diago Miguel, et al. · Clinical oral investigations PMID:31612327 | 2020 | 2 | 2 | not extracted yet |
| Comparative analysis of platelet-rich fibrin, platelet-rich fibrin with hydroxyapatite and platelet-rich fibrin with alendronate in bone… Tiwari 2021 · Tiwari Urvashi Ojha, Chandra Ramesh, et al. · Journal of conservative dentistry : JCD PMID:33623234 | 2020 | 2 | none stated | not extracted yet |
| Evaluation of Blood Clot, Platelet-rich Plasma, Platelet-rich Fibrin, and Platelet Pellet as Scaffolds in Regenerative Endodontic Treatment: A… Ulusoy 2019 · Ulusoy Ayca Tuba, Turedi Irem, et al. · Journal of endodontics PMID:30935618 | 2019 | 2 | 6 | not extracted yet |
| Healing potentiality of blood clot, S-PRF and A-PRF as scaffold in treatment of non-vital mature single rooted teeth with chronic peri-apical… Darwish 2025 · Darwish Omnia Badawy, Aziz Said Mohamed Abdel, et al. · BMC oral health PMID:39789544 | 2025 | 1 | 2 | not extracted yet |
| Regenerative potential of concentrated growth factor compared to platelet-rich fibrin in treatment of necrotic mature teeth: a randomized clinical… Salah 2025 · Salah Taghreed, Hussein Wael, et al. · BDJ open PMID:39900647 | 2025 | 1 | none stated | not extracted yet |
| Change in the size of apical radiolucencies in adolescent's mature maxillary incisors following retreatment with two regenerative endodontic… Wahba 2025 · Wahba Norhan Khaled Omar, Bahnasy Sherif Shafik E L, et al. · Clinical oral investigations PMID:40319119 | 2025 | 1 | none stated | not extracted yet |
| Comparative Evaluation of Advanced Platelet-Rich Fibrin and Blood Clot as Scaffolds in Regenerative Endodontics for Immature Necrotic Teeth: A… Qamar 2025 · Qamar Seema, Mondal Arnab, et al. · Journal of pharmacy & bioallied sciences PMID:40655730 | 2025 | 1 | none stated | not extracted yet |
| The use of concentrated growth factors in guiding bone regeneration after microsurgical endodontic surgery for periapical lesions. Lin 2025 · Lin Qi, Liu Shaofeng, et al. · Regenerative biomaterials PMID:41018924 | 2025 | 1 | none stated | not extracted yet |
| Evaluation of the efficacy of injectable platelet-rich fibrin versus platelet-rich plasma in the regeneration of traumatized necrotic immature… Mohamed 2024 · Abo-Heikal Maha Mohamed, El-Shafei Jealan M, et al. · Dental traumatology : official publication of International Association for Dental Traumatology PMID:37612879 | 2024 | 1 | none stated | not extracted yet |
| A 12-month randomized controlled trial to assess the efficacy of revitalization of retreated mature incisors with periapical radiolucency in… Elheeny 2024 · Elheeny Ahmad Abdel Hamid, Hussien Osama Seif-Elnasr, et al. · Scientific reports PMID:39013938 | 2024 | 1 | 2 | not extracted yet |
| Clinical and radiographic evaluation of regenerative endodontic procedures (REPs) with or without concentrated growth factor (CGF) as scaffolds for… Zhang 2024 · Zhang Yanfei, Sheng Min · The Journal of clinical pediatric dentistry PMID:39087227 | 2024 | 1 | none stated | not extracted yet |
| Comparative Evaluation of Platelet-rich Fibrin and Treated Dentin Matrix in Regenerative Endodontic Treatment of Nonvital Immature Permanent Teeth:… Asal 2024 · Asal Mohamed A, Elkalla Ibrahim H, et al. · The journal of contemporary dental practice PMID:39364823 | 2024 | 1 | none stated | not extracted yet |
| Application of Three Types of Scaffolds in Pulp Regeneration for Permanent Mature Teeth with Periapical Lesions: A Randomized Controlled Trial. Alshahhoud 2024 · Alshahhoud Aliaa, Rekab Mohamad Salem, et al. · European endodontic journal PMID:39704629 | 2024 | 1 | none stated | not extracted yet |
| Comparison of double antibiotic chitosan hydrogel scaffold with platelet-rich fibrin in regeneration in immature necrotic permanent teeth -… Mittal 2024 · Mittal Neelam, Baranwal Harakh Chand, et al. · Journal of conservative dentistry and endodontics PMID:39959016 | 2024 | 1 | none stated | not extracted yet |
| Application of platelet-rich fibrin and freeze-dried bone allograft following apicoectomy: A comparative assessment of radiographic healing. Garg 2023 · Garg Madhur, Srivastava Vipul, et al. · Indian journal of dental research : official publication of Indian Society for Dental Research PMID:37417055 | 2023 | 1 | none stated | not extracted yet |
| Comparative evaluation of bioglass nanofiber, dexamethasone-coated bioglass nanofiber, and platelet-rich fibrin, as scaffolds in regenerative… Gupta 2022 · Gupta Sakshi, Mittal Neelam, et al. · Journal of conservative dentistry : JCD PMID:36506625 | 2022 | 1 | none stated | not extracted yet |
| Evaluation of blood clot, platelet-rich plasma, and platelet-rich fibrin-mediated regenerative endodontic procedures in teeth with periapical… Markandey 2022 · Markandey Swati, Das Adhikari Haridas · Restorative dentistry & endodontics PMID:36518608 | 2022 | 1 | none stated | not extracted yet |
| Comparative Evaluation of Platelet-rich Fibrin and Concentrated Growth Factor as Scaffolds in Regenerative Endodontic Procedure: A Randomized… Kavitha 2022 · Kavitha Mahendran, Shakthipriya Sivaprakasam, et al. · The journal of contemporary dental practice PMID:37125518 | 2022 | 1 | none stated | not extracted yet |
| Regenerative Endodontic Procedure of Immature Permanent Teeth with Leukocyte and Platelet-rich Fibrin: A Multicenter Controlled Clinical Trial. Meschi 2021 · Meschi Nastaran, EzEldeen Mostafa, et al. · Journal of endodontics PMID:34400199 | 2021 | 1 | none stated | not extracted yet |
| Assessment of pulp sensibility in the mature necrotic teeth using regenerative endodontic therapy with various scaffolds - Randomised clinical trial. Mittal 2021 · Mittal Neelam, Baranwal Harakh C, et al. · Indian journal of dental research : official publication of Indian Society for Dental Research PMID:34810392 | 2021 | 1 | 1 | not extracted yet |
| Fenestrated endovascular aneurysm repair with concomitant horseshoe kidney. Major 2025 · Peters Danielle, Obmann Melissa, et al. · Journal of vascular surgery cases and innovative techniques PMID:32025598 | 2020 | 1 | 1 | not extracted yet |
| The effect of platelet-rich plasma as a scaffold in regeneration/revitalization endodontics of immature permanent teeth assessed using 2-dimensional… ElSheshtawy 2020 · ElSheshtawy A S, Nazzal H, et al. · International endodontic journal PMID:32249441 | 2020 | 1 | none stated | not extracted yet |
| Impact of Platelet-rich Plasma in the Healing of Through-and-through Periapical Lesions Using 2-dimensional and 3-dimensional Evaluation: A… Dhamija 2020 · Dhamija Ritika, Tewari Sanjay, et al. · Journal of endodontics PMID:32553878 | 2020 | 1 | 1 | not extracted yet |
| Comparative evaluation of Platelet Rich Plasma (PRP) versus Platelet Rich Fibrin (PRF) scaffolds in regenerative endodontic treatment of immature… Rizk 2020a · Rizk Hazim Mohamed, Salah Al-Deen Mohamed Sherif Mohamed, et al. · The Saudi dental journal PMID:32647469 | 2020 | 1 | none stated | not extracted yet |
| Pulp Revascularization/Revitalization of Bilateral Upper Necrotic Immature Permanent Central Incisors with Blood Clot vs Platelet-rich Fibrin… Rizk 2020b · Rizk Hazim Mohamed, Salah Al-Deen Mohamed Sherif, et al. · International journal of clinical pediatric dentistry PMID:33149405 | 2020 | 1 | none stated | not extracted yet |
| Comparative Study between Revitalization of Necrotic Immature Permanent Anterior Teeth with and without Platelet Rich Fibrin: A Randomized… Ragab 2019 · Ragab Rasha Adel, Lattif Amr Ezzat Abd El, et al. · The Journal of clinical pediatric dentistry PMID:30730794 | 2019 | 1 | none stated | not extracted yet |
| Regenerative Endodontic Treatment of Bilateral Necrotic Immature Permanent Maxillary Central Incisors with Platelet-rich Plasma versus Blood Clot: A… Rizk 2019 · Rizk Hazim Mohamed, Al-Deen Mohamed Sherif Salah, et al. · International journal of clinical pediatric dentistry PMID:31866720 | 2019 | 1 | none stated | not extracted yet |
| Comparison of the Effect of PRP, PRF and Induced Bleeding in the Revascularization of Teeth with Necrotic Pulp and Open Apex: A Triple Blind… Shivashankar 2017 · Shivashankar Vasundara Yayathi, Johns Dexton Antony, et al. · Journal of clinical and diagnostic research : JCDR PMID:28765825 | 2017 | 1 | 1 | not extracted yet |
| Efficacy of platelet-rich plasma as a scaffold in regenerative endodontic treatment. Bezgin 2015 · Bezgin Tugba, Yilmaz Ayca Dilara, et al. · Journal of endodontics PMID:25459571 | 2015 | 1 | 1 | not extracted yet |
| Effect of platelet concentrate on quality of life after periradicular surgery: a randomized clinical study. Del Fabbro 2012 · Del Fabbro Massimo, Ceresoli Valentina, et al. · Journal of endodontics PMID:22595104 | 2012 | 1 | none stated | not extracted yet |
| Revascularization with and without platelet-rich plasma in nonvital, immature, anterior teeth: a pilot clinical study. Jadhav 2012 · Jadhav Ganesh, Shah Naseem, et al. · Journal of endodontics PMID:23146641 | 2012 | 1 | none stated | not extracted yet |
| Angerame 2015 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| El-Kabbaney 2021 matched by author and year (probable) | NR | 1 | 1 | not extracted yet |
| Major 2025 matched by author and year (probable) | NR | 1 | 1 | not extracted yet |