evidencegaps
Primary study · included by 2 reviews

Impact of Advanced Platelet-Rich Fibrin on Early Bone Healing After Endodontic Microsurgery: A Randomized Controlled Trial.

Karkle 2025 · Karkle Aleksandra, Neimane Laura, Zolovs Maksims, et al. · Diagnostics (Basel, Switzerland) · 2025

Included by

Clinical Outcomes of Platelet-Rich Fibrin in Endodontic Microsurgery: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Karkle 2025 · Table 2; Table 3; Figure 3; reference list
Outcome this study informsPooled effectEvidenceCertainty
Clinical-radiographic healing success
Platelet-rich fibrin or its derivatives (L-PRF, A-PRF, A-PRF+, i-PRF, PRF membrane) as adjunct to endodontic microsurgery vs Endodontic microsurgery without PRF (conventional surgery/control)
OR 1.223 [0.303, 4.931]3 studies · 96 participantsVery low
Context-dependent effectiveness of autologous platelet concentrates in regenerative endodontic procedures and periapical surgery: A systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Karkle 2025 · Table 1; reference 23

The review does not say which of its outcomes this study informs.

2 including reviews in total.