Primary study · included by 1 review
Healing potentiality of blood clot, S-PRF and A-PRF as scaffold in treatment of non-vital mature single rooted teeth with chronic peri-apical periodontitis following regenerative endodontic therapy: randomized clinical trial.
Darwish 2025 · Darwish Omnia Badawy, Aziz Said Mohamed Abdel, Sadek Hany Samy · BMC oral health · 2025
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Pulp sensibility (positive response) APC-based regenerative endodontic procedure (PRP, S-PRF, A-PRF, PRF) vs Control: conventional endodontic treatment or retreatment, or blood clot scaffold · 12 to 18 months follow-up | RR 5.31 [0.00, 1421155.98] | 3 studies · 183 participants | Very low |
Radiographic healing (clinical and/or radiographic success) APC-based regenerative endodontic procedure (PRP, S-PRF, A-PRF, PRF) vs Control: conventional endodontic treatment or retreatment, or blood clot scaffold · 12 to 18 months follow-up | RR 0.99 [0.70, 1.40] | 3 studies · 142 participants | Moderate |
1 including review in total.