Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Inflammatory Biomarkers in Irreversible Pulpitis and Pulp Necrosis: A Systematic Review and Meta-Analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Expression of calcitonin gene-related peptide and pulp sensitivity tests in irreversible pulpitis. Castillo-Silva 2019 · Castillo-Silva Brenda Eréndida, Martínez-Jiménez Verónica, et al. · Brazilian oral research PMID:31531564 | 2019 | 2 | 1 | not extracted yet |
| Substance P and CGRP expression in dental pulps with irreversible pulpitis. Sattari 2010 · Sattari Mandana, Mozayeni Mohammad Ali, et al. · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc PMID:20666750 | 2010 | 2 | 2 | not extracted yet |
| Calcitonin gene-related peptide receptor expression in alternatively activated monocytes/macrophages during irreversible pulpitis. Caviedes-Bucheli 2008 · Caviedes-Bucheli Javier, Moreno Gloria Cristina, et al. · Journal of endodontics PMID:18634925 | 2008 | 2 | none stated | not extracted yet |
| Quantification of neuropeptides (calcitonin gene-related peptide, substance P, neurokinin A, neuropeptide Y and vasoactive intestinal polypeptide)… Caviedes-Bucheli 2006 · Caviedes-Bucheli J, Lombana N, et al. · International endodontic journal PMID:16640639 | 2006 | 2 | 2 | not extracted yet |
| Calcitonin gene-related peptide receptor expression in healthy and inflamed human pulp tissue. Caviedes-Bucheli 2005 · Caviedes-Bucheli J, Arenas N, et al. · International endodontic journal PMID:16164685 | 2005 | 2 | none stated | not extracted yet |
| Expression of calcitonin gene-related peptide (CGRP) in irreversible acute pulpitis. Caviedes-Bucheli 2004 · Caviedes-Bucheli Javier, Camargo-Beltrán Carolina, et al. · Journal of endodontics PMID:15085045 | 2004 | 2 | 1 | not extracted yet |
| Tissue levels of immunoreactive substance P are increased in patients with irreversible pulpitis. Bowles 2003 · Bowles Walter R, Withrow John C, et al. · Journal of endodontics PMID:12701777 | 2003 | 2 | 1 | not extracted yet |
| Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in pulp tissue from painful and healthy human teeth. Awawdeh, Lundy 2002 · Awawdeh L, Lundy F T, et al. · International endodontic journal PMID:11853236 | 2002 | 2 | 2 | not extracted yet |
| Jain 2024 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Sharma 2021 matched by author and year (probable) | NR | 2 | 1 | not extracted yet |
| Cytokine expression of IL-8 before and after root canal treatment in patients with symptomatic apical periodontitis: A clinical trial. Abouelenien 2024 · Abouelenien Sarah Samir, Shaker Olfat Gamil, et al. · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc PMID:37818971 | 2024 | 1 | none stated | not extracted yet |
| Expression of Selected Inflammatory Mediators with Different Clinical Characteristics of Pulpal Inflammation. Sabeti M.A. 2024 · Sabeti Mohammad A, Nikghalb Keyvan D, et al. · Journal of endodontics PMID:38147909 | 2024 | 1 | none stated | not extracted yet |
| Discriminatory performance of the pulpal inflammatory biomarkers; Interleukin-8 and TNF-α in patients with symptoms indicative of reversible and… Nawal 2024 · Nawal Ruchika Roongta, Yadav Sudha, et al. · International endodontic journal PMID:38703070 | 2024 | 1 | none stated | not extracted yet |
| Influence of Diclofenac Potassium versus Prednisolone on Postendodontic Pain and Pulpal Interleukin-8 Expression in Symptomatic Irreversible… Soliman A.A. 2024 · Soliman Ahmed Adel, Ezzat Khaled Mohamed, et al. · Journal of endodontics PMID:38925367 | 2024 | 1 | none stated | not extracted yet |
| Comparision of interleukin-1β concentrations in posttreatment endodontic disease and other pulpal and periapical conditions - A clinical study. Jain S 2024 · Jain Shivangi, Sundar Sathish, et al. · Journal of conservative dentistry and endodontics PMID:39372575 | 2024 | 1 | none stated | not extracted yet |
| Comparison of ADAMTS Levels in Pulp Tissue Samples of Healthy and Symptomatic Irreversible Pulpitis Teeth. Golbasi 2022 · Golbasi Filiz, Erdemir Ali, et al. · Journal of endodontics PMID:34914940 | 2022 | 1 | none stated | not extracted yet |
| The detection of pro-inflammatory cytokines in exudates from dental pulp tissues. Wu 2022 · Wu Qianqian, Li Shanshan, et al. · Cytokine PMID:35255379 | 2022 | 1 | none stated | not extracted yet |
| Correlation between Transforming Growth Factor-β and Periapical Lesions in Patients with Chronic Apical Periodontitis. Li 2022 · Li Xiujuan, Han Xuesong, et al. · Journal of healthcare engineering PMID:35360476 | 2022 | 1 | none stated | not extracted yet |
| Association between concentration of active MMP-9 in pulpal blood and pulpotomy outcome in permanent mature teeth with irreversible pulpitis - a… Sharma 2021 · Sharma R, Kumar V, et al. · International endodontic journal PMID:33128238 | 2021 | 1 | none stated | not extracted yet |
| Cytokines and chemokines associated with Treg/Th17 response in chronic inflammatory periapical disease. Toledo 2019 · Toledo André Oliveira Naufel de, Couto Aline Maria do, et al. · Brazilian oral research PMID:31664358 | 2019 | 1 | none stated | not extracted yet |
| Comparison of IL-1β, TNF-α, hBD-2, and hBD-3 Expression in the Dental Pulp of Smokers Versus Nonsmokers. Ayoub 2017 · Ghattas Ayoub Caroline, Aminoshariae Anita, et al. · Journal of endodontics PMID:29033092 | 2017 | 1 | none stated | not extracted yet |
| A Prospective Clinical Pilot Study on the Level of Matrix Metalloproteinase-9 in Dental Pulpal Blood as a Marker for the State of Inflammation in… Mente 2016 · Mente Johannes, Petrovic Jelena, et al. · Journal of endodontics PMID:26725178 | 2016 | 1 | none stated | not extracted yet |
| Catalase activity in healthy and inflamed pulp tissues of permanent teeth in young people. Topçu 2016 · Topcu Kmc, Kırıcı D Ö, et al. · Nigerian journal of clinical practice PMID:27538547 | 2016 | 1 | none stated | not extracted yet |
| Methyl mercaptan and hydrogen sulfide products stimulate proinflammatory cytokines in patients with necrotic pulp tissue and endodontically treated… Gresser 2015 · Jacobi-Gresser E, Schütt S, et al. · Journal of biological regulators and homeostatic agents PMID:25864743 | 2015 | 1 | none stated | not extracted yet |
| Cytokines as diagnostic markers of pulpal inflammation. ElSalhy 2013 · Elsalhy M, Azizieh F, et al. · International endodontic journal PMID:23240887 | 2013 | 1 | none stated | not extracted yet |
| Osteocalcin expression in pulp inflammation. Abd-Elmegui 2013 · Abd-Elmeguid Ashraf, Abdeldayem Marwa, et al. · Journal of endodontics PMID:23791253 | 2013 | 1 | none stated | not extracted yet |
| Evaluation of gelatinases, tissue inhibitor of matrix metalloproteinase-2, and myeloperoxidase protein in healthy and inflamed human dental pulp… Accorsi-Mendonça 2013 · Accorsi-Mendonça Thais, Silva Emmanuel João Nogueira Leal, et al. · Journal of endodontics PMID:23791255 | 2013 | 1 | none stated | not extracted yet |
| Interleukin-8 is increased in gingival crevicular fluid from patients with acute pulpitis. Karapanou 2008 · Karapanou Virginia, Kempuraj Duraisamy, et al. · Journal of endodontics PMID:18215670 | 2008 | 1 | none stated | not extracted yet |
| Copper-zinc superoxide dismutase activity in healthy and inflamed human dental pulp. Varvara 2005 · Varvara G, Traini T, et al. · International endodontic journal PMID:15743423 | 2005 | 1 | none stated | not extracted yet |
| Effect of an intraosseous injection of depo-medrol on pulpal concentrations of PGE2 and IL-8 in untreated irreversible pulpitis. Isett 2003 · Isett James, Reader Al, et al. · Journal of endodontics PMID:12701778 | 2003 | 1 | none stated | not extracted yet |
| Catalase activity in human healthy and inflamed dental pulps. Esposito 2003 · Esposito P, Varvara G, et al. · International endodontic journal PMID:12950573 | 2003 | 1 | none stated | not extracted yet |
| Evaluating IL-2 levels in human pulp tissue. Anderson 2002 · Anderson Lisa M, Dumsha Thom C, et al. · Journal of endodontics PMID:12236309 | 2002 | 1 | none stated | not extracted yet |
| Detection of tumor necrosis factor alpha in normal and inflamed human dental pulps. Pezelj-Ribaric 2002 · Pezelj-Ribaric Sonja, Anic Ivica, et al. · Archives of medical research PMID:12459320 | 2002 | 1 | none stated | not extracted yet |
| Aspartate aminotransferase activity in human healthy and inflamed dental pulps. Spoto 2001 · Spoto G, Fioroni M, et al. · Journal of endodontics PMID:11487132 | 2001 | 1 | none stated | not extracted yet |
| Bradykinin levels in dental pulp by microdialysis. Lepinski 2000 · Lepinski A M, Hargreaves K M, et al. · Journal of endodontics PMID:11471646 | 2000 | 1 | none stated | not extracted yet |
| Detection of interleukin-6 in human dental pulp and periapical lesions. Barkhordar 1999 · Barkhordar R A, Hayashi C, et al. · Endodontics & dental traumatology PMID:10219150 | 1999 | 1 | none stated | not extracted yet |
| Increased interleukin-8 expression in inflamed human dental pulps. Huang 1999 · Huang G T, Potente A P, et al. · Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics PMID:10468466 | 1999 | 1 | none stated | not extracted yet |
| Detection of human IL-2 in normal and inflamed dental pulps. Rauschenberger 1997 · Rauschenberger C R, Bailey J C, et al. · Journal of endodontics PMID:9545944 | 1997 | 1 | none stated | not extracted yet |
| Quantitative analysis of immunoglobulins and inflammatory factors in human pulpal blood from exposed pulps. Nakanishi 1995 · Nakanishi T, Matsuo T, et al. · Journal of endodontics PMID:7561655 | 1995 | 1 | none stated | not extracted yet |
| Determination and relationship of C-reactive protein in human dental pulps and in serum. Proctor 1991 · Proctor M E, Turner D W, et al. · Journal of endodontics PMID:1940751 | 1991 | 1 | none stated | not extracted yet |
| Abd-Elmeguid 2013 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Abouelenien 2024 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Accorsi-Mendonça 2013 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Akbal Dincer 2020 matched by author and year (probable) | NR | 1 | 1 | not extracted yet |
| Anderson 2002 matched by author and year (probable) | NR | 1 | 1 | not extracted yet |
| Awawdeh 2002 matched by author and year (probable) | NR | 1 | 2 | not extracted yet |
| Awawdeh 2002 (PGE2) matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Ayoub 2017 matched by author and year (probable) | NR | 1 | 3 | not extracted yet |
| Barkhordar 1999 matched by author and year (probable) | NR | 1 | 1 | not extracted yet |
| Bowles 2003 matched by author and year (probable) | NR | 1 | 1 | not extracted yet |