evidencegaps
Primary study · included by 2 reviews

Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in pulp tissue from painful and healthy human teeth.

Awawdeh, Lundy 2002 · Awawdeh L, Lundy F T, Shaw C, et al. · International endodontic journal · 2002

Included by

Inflammatory Biomarkers in Irreversible Pulpitis and Pulp Necrosis: A Systematic Review and Meta-Analysis.
Non-Cochrane · aetiology · 2026 · cited as Awawdeh, Lundy 2002 · Table 1

The review does not say which of its outcomes this study informs.

Neural biomarkers in pulpitis and their associations with inflammation and pain perception: a systematic review and meta-analysis.
Non-Cochrane · prognostic · 2026 · cited as Awawdeh 2002 · Table 1; Fig. 3
Outcome this study informsPooled effectEvidenceCertainty
Calcitonin gene-related peptide (CGRP) expression level in dental pulp
Symptomatic irreversible pulpitis (inflamed pulp) vs Healthy pulp (normal pulp, NP)
SMD 2.973 [0.553, 5.393]5 studies · 188 participantsLow
Substance P (SP) expression level in dental pulp
Symptomatic irreversible pulpitis (inflamed pulp) vs Healthy pulp (normal pulp, NP)
SMD 3.108 [0.008, 6.208]4 studies · 127 participantsVery low

2 including reviews in total.