Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by The effect of pharmacological and non-pharmacological interventions on pain control after orthodontic treatment: a systematic review and…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Effect of supplemental vibration on orthodontic treatment with aligners: A randomized trial. Katchooi 2018 · Katchooi Mina, Cohanim Bobby, et al. · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PMID:29501108 | 2018 | 3 | 4 | not extracted yet |
| The effectiveness of low-level laser therapy and low-intensity pulsed ultrasound in reducing pain induced by orthodontic separation: a randomized… Al-Hanbali 2024 · Al-Hanbali Lama Mohammad Saffouh, Burhan Ahmad Sharafeddin, et al. · BMC oral health PMID:38308275 | 2024 | 2 | 1 | not extracted yet |
| Effect of low-level laser therapy on the time needed for leveling and alignment of mandibular anterior crowding. Ghaffar 2022 · Ghaffar Yasmine Khaled Abdel, El Sharaby Fouad A, et al. · The Angle orthodontist PMID:35344012 | 2022 | 2 | 4 | not extracted yet |
| Low-level laser therapy (830 nm) on orthodontic pain: blinded randomized clinical trial. Martins 2019 · Martins Isabela Parsekian, Martins Renato Parsekian, et al. · Lasers in medical science PMID:29998356 | 2019 | 2 | none stated | not extracted yet |
| Evaluation of Low-Level Laser Therapy on Orthodontic Tooth Movement: A Randomized Control Study. Guram 2018 · Guram Guneet, Reddy Rajesh Kumar, et al. · Contemporary clinical dentistry PMID:29599594 | 2018 | 2 | 2 | not extracted yet |
| Effects of low-level laser irradiation on the rate of orthodontic tooth movement and associated pain with self-ligating brackets. Qamruddin 2017 · Qamruddin Irfan, Alam Mohammad Khursheed, et al. · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PMID:29103440 | 2017 | 2 | 1 | not extracted yet |
| Acetaminophen Versus Liquefied Ibuprofen for Control of Pain During Separation in Orthodontic Patients: A Randomized Triple Blinded Clinical Trial. Hosseinzadeh Nik 2016 · Hosseinzadeh Nik Tahereh, Shahsavari Negin, et al. · Acta medica Iranica PMID:27424011 | 2016 | 2 | none stated | not extracted yet |
| Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial. Zarif Najafi 2015 · Zarif Najafi Hooman, Oshagh Morteza, et al. · Progress in orthodontics PMID:26467790 | 2015 | 2 | 5 | not extracted yet |
| Controlling pain during orthodontic fixed appliance therapy with non-steroidal anti-inflammatory drugs (NSAID): a randomized, double-blinded,… Gupta 2014 · Gupta Mudit, Kandula Srinivas, et al. · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie PMID:25355194 | 2014 | 2 | none stated | not extracted yet |
| The effects of a vibrational appliance on tooth movement and patient discomfort: a prospective randomised clinical trial. Miles 2012 · Miles Peter, Smith Heath, et al. · Australian orthodontic journal PMID:23304970 | 2012 | 2 | none stated | not extracted yet |
| Comparison of the efficacy of ibuprofen and acetaminophen in controlling pain after orthodontic tooth movement. Salmassian 2009 · Salmassian Reza, Oesterle Larry J, et al. · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PMID:19361739 | 2009 | 2 | none stated | not extracted yet |
| Pain control during fixed orthodontic appliance therapy. Polat 2005 · Polat Omur, Karaman Ali Ihya · The Angle orthodontist PMID:15825785 | 2005 | 2 | 3 | not extracted yet |
| Effect of transcutaneous electrical nerve stimulation for controlling pain associated with orthodontic tooth movement. Roth 1986 · Roth P M, Thrash W J · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PMID:3488674 | 1986 | 2 | none stated | not extracted yet |
| Ghaffar 2022 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Guram 2018 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Katchooi 2018 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Kaur 2019 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Acupressure versus NSAID for relief of orthodontic pain : A randomized controlled clinical trial. Elshehaby 2025 · Elshehaby Moataz, Ali Tawfik Marwa, et al. · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie PMID:37395765 | 2025 | 1 | none stated | not extracted yet |
| Low-level laser therapy and laser acupuncture therapy for pain relief after initial archwire placement : A randomized clinical trial. Ahrari 2024 · Ahrari Farzaneh, Shafaee Hooman, et al. · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie PMID:38683401 | 2024 | 1 | none stated | not extracted yet |
| Comparative efficacy of pharmaceutical (Ibuprofen) and non-pharmaceutical (photobiomodulation, and chewing gum) interventions for pain reduction… Azizi 2024 · Azizi Fatemeh, Zaseh Maryam Malekpour Salim, et al. · Lasers in medical science PMID:39317795 | 2024 | 1 | none stated | not extracted yet |
| The efficacy of low-level laser therapy versus paracetamol-caffeine in controlling orthodontic separation pain and changes in the… Owayda 2022 · Owayda Amer M, Hajeer Mohammad Y, et al. · Journal of the World federation of orthodontists PMID:35110003 | 2022 | 1 | none stated | not extracted yet |
| Mechanical Vibration and Chewing Gum Methods in Orthodontic Pain Relief. Celebi 2022 · Çelebi Fatih · Turkish journal of orthodontics PMID:35788438 | 2022 | 1 | none stated | not extracted yet |
| Effects of ibuprofen and low-level laser therapy on orthodontic pain by means of the analysis of interleukin 1-beta and substance P levels in the… Kaya 2021 · Kaya Yeşim, Alkan Özer, et al. · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie PMID:33097977 | 2021 | 1 | none stated | not extracted yet |
| Efficacy of Photobiomodulation Therapy for Orthodontic Pain Control Following the Placement of Elastomeric Separators: A Randomized Clinical Trial. Mirhashemi 2021 · Mirhashemi AmirHossein, Rasouli Seyedreza, et al. · Journal of lasers in medical sciences PMID:34084734 | 2021 | 1 | none stated | not extracted yet |
| Effectiveness of low-level laser therapy and chewing gum in reducing orthodontic pain: A randomized controlled trial. Celebi 2021 · Celebi Fatih, Bicakci Ali Altug, et al. · Korean journal of orthodontics PMID:34556585 | 2021 | 1 | none stated | not extracted yet |
| Low-level laser-aided orthodontic treatment of periodontally compromised patients: a randomised controlled trial. Ren 2020 · Ren Chong, McGrath Colman, et al. · Lasers in medical science PMID:31833004 | 2020 | 1 | none stated | not extracted yet |
| Assessment of a single versus double application of low-level laser therapy in pain reduction following orthodontic elastomeric separation: A… Almallah Hasan 2020 · Almallah Mai Mohammed Erfan, Hajeer Mohammad Younis, et al. · Dental and medical problems PMID:32307932 | 2020 | 1 | none stated | not extracted yet |
| Low-level laser therapy effectiveness in reducing initial orthodontic archwire placement pain in premolars extraction cases: a single-blind,… Hasan 2020 · AlSayed Hasan Mohammad Moaffak A, Sultan Kinda, et al. · BMC oral health PMID:32690001 | 2020 | 1 | none stated | not extracted yet |
| Low-Level Laser Therapy: A Noninvasive Method of Relieving Postactivation Orthodontic Pain-A Randomized Controlled Clinical Trial. Prasad 2019 · Prasad Subramaniam Murugesan Vignesh, Prasanna Turuvekere Ramaiah, et al. · Journal of pharmacy & bioallied sciences PMID:31198342 | 2019 | 1 | none stated | not extracted yet |
| Effects of single-dose, low-level laser therapy on pain associated with the initial stage of fixed orthodontic treatment: A randomized clinical trial. Qamruddin 2018 · Qamruddin Irfan, Alam Mohammad Khursheed, et al. · Korean journal of orthodontics PMID:29564218 | 2018 | 1 | none stated | not extracted yet |
| Effect of a single dose of low-level laser therapy on spontaneous and chewing pain caused by elastomeric separators. Qamruddin 2016 · Qamruddin Irfan, Alam Mohammad Khursheed, et al. · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PMID:26718379 | 2016 | 1 | none stated | not extracted yet |
| Evaluation of Low Level Laser Therapy on Pain Perception Following Orthodontic Elastomeric Separation: A Randomized Controlled Trial. Almallah 2016 · Almallah Mai M E, Almahdi Wael H, et al. · Journal of clinical and diagnostic research : JCDR PMID:28050498 | 2016 | 1 | none stated | not extracted yet |
| Pain reduced by low-level laser therapy during use of orthodontic separators in early mixed dentition. Stein 2015 · Stein Steffen, Korbmacher-Steiner Heike, et al. · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie PMID:26272170 | 2015 | 1 | none stated | not extracted yet |
| The effect of 810-nm low-level laser therapy on pain caused by orthodontic elastomeric separators. Eslamian 2014 · Eslamian Ladan, Borzabadi-Farahani Ali, et al. · Lasers in medical science PMID:23334785 | 2014 | 1 | none stated | not extracted yet |
| Effect of frequent laser irradiation on orthodontic pain. A single-blind randomized clinical trial. Kim 2013 · Kim Won Tae, Bayome Mohamed, et al. · The Angle orthodontist PMID:23241006 | 2013 | 1 | none stated | not extracted yet |
| Pain reduction after initial archwire placement in orthodontic patients: a randomized clinical trial. Farzanegan 2012 · Farzanegan Fahimeh, Zebarjad Seyed Mojtaba, et al. · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PMID:22284284 | 2012 | 1 | none stated | not extracted yet |
| Effectiveness of piroxicam and ibuprofen premedication on orthodontic patients' pain experiences. Kohli 2011 · Kohli Sarvraj Singh, Kohli Virinder Singh · The Angle orthodontist PMID:21644837 | 2011 | 1 | none stated | not extracted yet |
| Cryptococcosis in systemic lupus erythematosus: a series of six cases. Kohli 2011 · González L A, Vásquez G, et al. · Lupus PMID:20118161 | 2010 | 1 | none stated | not extracted yet |
| The influence of a structured telephone call on orthodontic pain and anxiety. Bartlett 2005 · Bartlett Brian W, Firestone Allen R, et al. · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PMID:16214624 | 2005 | 1 | none stated | not extracted yet |
| Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain. Polat 2005 (preoperative ibuprofen and naproxen) · Polat Omur, Karaman Ali Ihya, et al. · The Angle orthodontist PMID:16279825 | 2005 | 1 | none stated | not extracted yet |
| Application of photodynamic oxidation to the disinfection of tapwater, seawater, and sewage contaminated with poliovirus. Kaur 2019 · Gerba C P, Wallis C, et al. · Photochemistry and photobiology PMID:201951 | 1977 | 1 | none stated | not extracted yet |
| Ahrari 2024 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Alansari 2018 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Almallah 2016 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Almallah Hasan 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Azizi 2024 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Bartlett 2005 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Celebi 2021 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Çelebi 2022 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Elshehaby 2025 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |