Primary study · included by 2 reviews

Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial.

Zarif Najafi 2015 · Zarif Najafi Hooman, Oshagh Morteza, Salehi Parisa, et al. · Progress in orthodontics · 2015

Included by

The effect of pharmacological and non-pharmacological interventions on pain control after orthodontic treatment: a systematic review and network meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Najaf 2015 · Table 1; References

The review does not say which of its outcomes this study informs.

Effectiveness of acetaminophen in comparison with ibuprofen for pain control in orthodontic patients: A systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Zarif Najafi 2015 · Figure 3A

Outcome this study informs	Pooled effect	Evidence	Certainty
Pain at rest (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 24 hours	MD 0.11 [-0.38, 0.6]	3 studies · 206 participants	Moderate
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 48 hours	MD -0.69 [-1.44, 0.06]	4 studies · 237 participants	Moderate
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 24 hours	MD 0.35 [-2.42, 3.12]	2 studies · 70 participants	GRADE not reported
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 24 hours	MD -0.53 [-1.46, 0.41]	2 studies · 167 participants	GRADE not reported
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 6 hours	MD -0.25 [-1.09, 0.59]	3 studies · 207 participants	Moderate
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 24 hours	MD 0.36 [-1.25, 1.98]	3 studies	GRADE not reported
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 24 hours	MD -0.66 [-1.49, 0.17]	3 studies	GRADE not reported
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 24 hours	MD 0.23 [-1.68, 2.15]	3 studies	GRADE not reported
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 24 hours	MD 0.01 [-1.36, 1.38]	4 studies · 237 participants	Very low
Pain during chewing (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 24 hours	MD 0.05 [-1.62, 1.72]	3 studies	GRADE not reported
Pain at rest (VAS 0 to 10) Acetaminophen (paracetamol) for pain control vs Ibuprofen for pain control · 48 hours	MD -0.48 [-1.12, 0.17]	3 studies · 206 participants	Moderate

2 including reviews in total.