Non-Cochrane · aetiology · PM42424341

The Association Between eHealth Literacy and Health Behaviors During and Since the COVID-19 Pandemic: Systematic Review and Meta-Analysis.

Ruan Boyu, Tian Jiashuai, Wang Xiaoyuan, et al. · Journal of medical Internet research · 2026 · PubMed · doi:10.2196/94233

Findings

24 findings

Population
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Patient status: patient populations
R 0.46 [0.37, 0.53]
GRADE not reported
3 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Income level: high-income economies
R 0.46 [0.39, 0.53]
GRADE not reported
4 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Health behavior domain: health management behaviors
R 0.42 [0.31, 0.52]
GRADE not reported
4 studies
Participants in cross-sectional studies conducted during or since COVID-19 (2020 or later)Higher eHealth literacyContinuous eHealth literacy score (correlation)Health behaviors (any prespecified domain)
Cross-sectional (data collected 2020 or later) · Community and clinical samples; mostly Asia and Middle East · Geriatric status: Older-adult populations
R 0.40 [0.33, 0.46]
GRADE not reported
1 study
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Income level: low- and middle-income economies
R 0.41 [0.31, 0.51]
GRADE not reported
6 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Geriatric status: younger or mixed-age populations
R 0.44 [0.37, 0.5]
GRADE not reported
9 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Health behavior domain: health-promoting behaviors
R 0.44 [0.36, 0.52]
GRADE not reported
6 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Overall, random effects without Knapp-Hartung (Appendix Table S1)
R 0.43 [0.37, 0.49]
GRADE not reported
10 studies
Participants in cross-sectional studies conducted during or since COVID-19 (2020 or later)Higher eHealth literacyContinuous eHealth literacy score (correlation)Health decision-making behaviors
Cross-sectional (data collected 2020 or later) · Community and clinical samples; mostly Asia and Middle East · Health behavior domain: Health decision-making behaviors
No correlation-based study contributed to this domain (0 studies)
No studies found
0 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Patient status: general populations
R 0.42 [0.34, 0.5]
GRADE not reported
7 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (continuous score)Lower eHealth literacy (correlation across the continuum)Health behaviors (health decision-making, health-promoting, health management)
Overall
R 0.43 [0.36, 0.51]
Very low
Downgraded: risk of bias, inconsistency
10 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (categorical, e.g. adequate or high)Lower eHealth literacy (categorical, e.g. inadequate or low)Health behaviors (health decision-making, health-promoting, health management)
Patient status: patient populations
OR 2.31 [0.89, 5.99]
GRADE not reported
2 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (categorical, e.g. adequate or high)Lower eHealth literacy (categorical, e.g. inadequate or low)Health behaviors (health decision-making, health-promoting, health management)
Income level: high-income economies
OR 2.25 [1.58, 3.2]
GRADE not reported
4 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (categorical, e.g. adequate or high)Lower eHealth literacy (categorical, e.g. inadequate or low)Health behaviors (health decision-making, health-promoting, health management)
Income level: low- and middle-income economies
OR 2.01 [1.17, 3.45]
GRADE not reported
2 studies
Participants in cross-sectional studies conducted during or since COVID-19 (2020 or later)Higher eHealth literacyLow versus high (inadequate versus adequate) eHealth literacyHealth-promoting behaviors
Cross-sectional (data collected 2020 or later) · Community and clinical samples; mostly Asia and Middle East · Health behavior domain: Health-promoting behaviors
OR 2.25 [1.58, 3.20]
GRADE not reported
4 studies
Participants in cross-sectional studies conducted during or since COVID-19 (2020 or later)Higher eHealth literacyLow versus high (inadequate versus adequate) eHealth literacyHealth decision-making behaviors (COVID-19 vaccine uptake)
Cross-sectional (data collected 2020 or later) · Community and clinical samples; mostly Asia and Middle East · Health behavior domain: Health decision-making behaviors
OR 2.70 [1.74, 4.19]
GRADE not reported
1 study
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (categorical, e.g. adequate or high)Lower eHealth literacy (categorical, e.g. inadequate or low)Health behaviors (health decision-making, health-promoting, health management)
Geriatric status: older-adult populations
OR 1.59 [1.21, 2.08]
GRADE not reported
2 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (categorical, e.g. adequate or high)Lower eHealth literacy (categorical, e.g. inadequate or low)Health behaviors (health decision-making, health-promoting, health management)
Geriatric status: nonolder-adult populations
OR 2.55 [1.85, 3.51]
GRADE not reported
4 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (categorical, e.g. adequate or high)Lower eHealth literacy (categorical, e.g. inadequate or low)Health behaviors (health decision-making, health-promoting, health management)
Overall
OR 2.12 [1.47, 3.05]
Low
6 studies
Participants in cross-sectional studies conducted during or since COVID-19 (2020 or later)Higher eHealth literacyLow versus high (inadequate versus adequate) eHealth literacyHealth management behaviors (medication adherence)
Cross-sectional (data collected 2020 or later) · Community and clinical samples; mostly Asia and Middle East · Health behavior domain: Health management behaviors
OR 1.55 [1.11, 2.17]
GRADE not reported
1 study
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (categorical, e.g. adequate or high)Lower eHealth literacy (categorical, e.g. inadequate or low)Health behaviors (health decision-making, health-promoting, health management)
Patient status: general populations
OR 2.18 [1.68, 2.83]
GRADE not reported
4 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (categorical, e.g. adequate or high)Lower eHealth literacy (categorical, e.g. inadequate or low)Health behaviors (health decision-making, health-promoting, health management)
Overall, random effects without Knapp-Hartung (Appendix Table S2)
OR 2.12 [1.64, 2.74]
GRADE not reported
6 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (per unit increase in score)Lower eHealth literacy (per unit decrease)Health behaviors (health decision-making, health-promoting, health management)
Overall, random effects without Knapp-Hartung (Appendix Table S3)
OR 1.07 [1.03, 1.12]
GRADE not reported
3 studies
People in observational studies with data collected in 2020 or later (COVID-19 and post-COVID-19 period)Higher eHealth literacy (per unit increase in score)Lower eHealth literacy (per unit decrease)Health behaviors (health decision-making, health-promoting, health management)
Overall
OR 1.07 [0.89, 1.3]
Very low
Downgraded: risk of bias, imprecision, inconsistency
3 studies

Included primary studies 31

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Chau 2026
Level of eHealth Literacy and Its Associations With Health Behaviors and Outcomes in Chinese Older Adults: Cross-Sectional Analysis of…
DOI:10.2196/74110
2026this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Chau 2026
Level of eHealth Literacy and Its Associations With Health Behaviors and Outcomes in Chinese Older Adults: Cross-Sectional Analysis of…
PMID:41616099
2026this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Choi 2021
eHealth Literacy, Awareness of Pandemic Infectious Diseases, and Healthy Lifestyle in Middle School Students.
PMID:34438590
2021this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Do 2020
Health Literacy, eHealth Literacy, Adherence to Infection Prevention and Control Procedures, Lifestyle Changes, and Suspected COVID-19…
DOI:10.2196/22894
2020this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Do 2020
Health Literacy, eHealth Literacy, Adherence to Infection Prevention and Control Procedures, Lifestyle Changes, and Suspected COVID-19…
PMID:33122164
2020this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Guo 2021
Socioeconomic Disparities in eHealth Literacy and Preventive Behaviors During the COVID-19 Pandemic in Hong Kong: Cross-sectional Study
DOI:10.2196/24577
2021this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Guo 2021
Socioeconomic Disparities in eHealth Literacy and Preventive Behaviors During the COVID-19 Pandemic in Hong Kong: Cross-sectional Study.
PMID:33784240
2021this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Guo 2024
Urban-Rural Differences in the Association of eHealth Literacy With Medication Adherence Among Older People With Frailty and Prefrailty:…
DOI:10.2196/54467
2024this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Guo 2024
Urban-Rural Differences in the Association of eHealth Literacy With Medication Adherence Among Older People With Frailty and Prefrailty:…
PMID:39259181
2024this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Hakeem 2023
The Association between Electronic Health Literacy and Oral Health Outcomes among Dental Patients in Saudi Arabia: A Cross-Sectional Study.
PMID:37372921
2023this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Jing 2021
DOI:10.11847/zgggws1134059
NRthis review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Kalayou 2022
Myth and Misinformation on COVID-19 Vaccine: The Possible Impact on Vaccination Refusal Among People of Northeast Ethiopia: A…
DOI:10.2147/rmhp.s366730
2022this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Kalayou 2022
Myth and Misinformation on COVID-19 Vaccine: The Possible Impact on Vaccination Refusal Among People of Northeast Ethiopia: A…
PMID:36213385
2022this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Kwon 2023
The relationship between depression, anxiety, e-health literacy, and health-promoting behavior in nursing students during COVID-19
DOI:10.1097/md.0000000000032809
2023this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Kwon 2023
The relationship between depression, anxiety, e-health literacy, and health-promoting behavior in nursing students during COVID-19.
PMID:36820579
2023this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Lee 2023
Associations of eHealth literacy and knowledge with preventive behaviours and psychological distress during the COVID-19 pandemic: a…
DOI:10.1136/bmjopen-2022-069514
2023this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Lee 2023
Associations of eHealth literacy and knowledge with preventive behaviours and psychological distress during the COVID-19 pandemic: a…
PMID:38101826
2023this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Li 2021
Associations Between Health Literacy, eHealth Literacy, and COVID-19–Related Health Behaviors Among Chinese College Students:…
DOI:10.2196/25600
2021this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Li 2021
Associations Between Health Literacy, eHealth Literacy, and COVID-19-Related Health Behaviors Among Chinese College Students:…
PMID:33822734
2021this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Moradi 2025
Differential Impact of eHealth Literacy on Wellness Behaviors of Iranian Nurses: Descriptive Correlational Cross-Sectional Study
DOI:10.2196/80792
2025this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Moradi 2025
Differential Impact of eHealth Literacy on Wellness Behaviors of Iranian Nurses: Descriptive Correlational Cross-Sectional Study.
PMID:41066644
2025this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Mousazadeh 2025
Association between health-promoting lifestyle and electronic health literacy among Iranian university students
DOI:10.1186/s12909-025-06823-6
2025this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Mousazadeh 2025
Association between health-promoting lifestyle and electronic health literacy among Iranian university students.
PMID:39955560
2025this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Qian 2024
Assessment of electronic health literacy and its association with self-management among gout patients: A cross-sectional study.
PMID:39507850
2024this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Rezakhani Moghaddam 2022
The role of e-health literacy and some cognitive factors in adopting protective behaviors of COVID-19 in Khalkhal residents.
PMID:35942262
2022this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Sun 2025
Correlation analysis of electronic health literacy, compliance behavior, and quality of life in middle-aged and older patients with…
PMID:41446526
2025this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Toyer Sahin 2026
The effects of e-Health and artificial intelligence literacy levels on disease self-management in patients with diabetes
DOI:10.1016/j.diabres.2026.113082
2026this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Toyer Sahin 2026
The effects of e-Health and artificial intelligence literacy levels on disease self-management in patients with diabetes.
PMID:41490818
2026this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Tran 2022
Predictors of eHealth Literacy and Its Associations with Preventive Behaviors, Fear of COVID-19, Anxiety, and Depression among…
PMID:35409448
2022this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Yu 2023
Association between eHealth literacy, diabetic behavior rating, and burden among caregivers of children with type 1 diabetes:…
DOI:10.1016/j.pedn.2023.08.012
2023this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet
Yu 2023
Association between eHealth literacy, diabetic behavior rating, and burden among caregivers of children with type 1 diabetes:…
PMID:37597400
2023this review onlyHealth behaviors (health decision-making, health-promoting, health management)not extracted yet

Review question

ElementPlanned (methods)Found (results)
PopulationHuman participants in observational studies with data collected in 2020 or later (during or since COVID-19)General and patient populations in 19 cross-sectional studies (China, Iran, South Korea, Turkey, Saudi Arabia, Ethiopia, Vietnam, Hong Kong); 3 studies of older-adult focus in grouped OR synthesis, 1 in correlation synthesis
InterventionHigher eHealth literacy assessed with a named instrument or clearly described operational measure with an explicit scoreHigher eHealth literacy, mostly measured with eHEALS (9 of 10 correlation studies; all grouped and continuous OR studies)
ComparisonLower eHealth literacy (categorical comparison) or per-unit increase in eHealth literacy score (continuous); correlation with behavior scoreLower eHealth literacy (grouped OR, n=6); per-unit eHealth literacy score (continuous OR, n=3); correlation (n=10)
OutcomesHealth behaviors classified a priori as health decision-making, health-promoting, or health management behaviorsHealth-promoting (correlation n=6, grouped OR n=4, continuous OR n=3), health management (correlation n=4, grouped OR n=1), health decision-making (grouped OR n=1) behaviors
Study designsObservational studies, cross-sectional designs eligibleCross-sectional studies (n=19)
TimingData collected 2020 or later; search January 1, 2020 to March 27, 2026Data collected 2020 to 2025