Cochrane · intervention · CD009376

Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis

Manresa, C, Sanz‐Miralles, EC, Twigg, J, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Oral HealthPeriodontology2 versionsAMSTAR 2: not assessed
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
18
current version
GRADE rated
7
No studies
9
Included studies
4
as reported
No studies 9 · 50%Ungraded 2 · 11.1%Very low 5 · 27.8%Low 2 · 11.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationAdult participants (18 years or older) previously treated for periodontal disease and now in the maintenance phase; treatment of active disease should have been concluded at least six months prior to randomisation to ensure participants were periodontally stable and compliantFour studies with 307 participants aged 31 to 85 years, previously treated for moderate to severe chronic periodontitis and recruited from an SPT programme (Preshaw 2005 at least 31 years; Tonetti 2012 at least 35 years; Lulic 2009 and Killeen 2016 at least 40 years)
InterventionSPT performed by periodontal specialists versus non-specialist dental professionals; SPT versus monitoring only, or alternative interventions that do not include mechanical debridement; SPT with and without adjunctive interventions delivered by dental professional or self-administered; SPT performed using different techniques and appliances for mechanical root debridement; SPT provided at different time intervalsSPT performed by specialists (n=1, Preshaw 2005); Mechanical debridement plus local antibiotic (n=2; Killeen 2016 minocycline microspheres, Tonetti 2012 doxycycline gel); Photodynamic therapy as an adjunct to mechanical debridement (n=1, Lulic 2009)
ComparisonNon-specialist dental professionals; Monitoring only; Alternative interventions that do not include mechanical debridement; With and without adjunctive interventions; Different techniques and appliances for mechanical root debridement; Different time intervals of SPTSPT performed by non-specialist clinicians / general dental practitioners (n=1); Mechanical debridement alone (n=3)
OutcomesPrimary outcomes: Tooth loss; Bleeding on probing (BoP); Clinical attachment level (CAL); Adverse events. Secondary outcomes: Probing pocket depth (PPD); Patient-reported outcome measures (e.g. satisfaction with treatment); Cost-effectiveness of SPT related to overall dental care with or without SPT; Cost-effectiveness of SPT related to the frequency of SPTTooth loss (n=0, not measured); Bleeding on probing (n=2 usable); Clinical attachment level (n=2); Probing pocket depth (n=4); Adverse events (n=2)
Study designsRandomised controlled trials (RCTs) with at least 12 months of follow-up; split-mouth studies with a risk of contamination were excludedRandomised controlled trials (n=4)
TimingAt least 12 months of follow-up. Follow-up was considered as the period of SPT in which the interventions were compared; it started following completion of active periodontal therapy or when participants had already been enrolled in a periodontal maintenance programmeAll four studies had a follow-up of at least 12 months

Search date: 2017-05. Databases: Cochrane Oral Health's Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE Ovid; Embase Ovid

Questions and results

Current version only

SPT performed by non-specialist clinicians (general dental practitioners under specialist prescription) vs SPT performed by specialists (specialist practice)

Population: Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
CD009376.PUB2 (current) · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Bleeding on probing (%)
12 months
MD 7.40 [-8.12, 22.92]
Mean BoP 36.7% (non-specialist) vs Mean BoP was 7.40% higher (8.12 lower to 22.92 higher)
1 study · 35 participantsVery low
Downgraded: risk of bias, imprecision
Tooth loss
Not measured0 studiesNo studies
Probing pocket depth (mm)
12 months
MD 0.20 [-0.40, 0.80]
Mean PPD 3.0 mm vs Mean PPD was 0.20 higher (0.40 lower to 0.80 higher)
1 study · 35 participantsVery low
Downgraded: risk of bias, imprecision
Clinical attachment loss
Not measured0 studiesNo studies
Adverse events
Not measured0 studiesNo studies

Supportive periodontal therapy (SPT) including mechanical debridement vs Monitoring only, or alternative interventions that do not include mechanical debridement

Population: Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
CD009376.PUB2 (current) · 1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
no estimate extracted0 studiesNo studies

SPT provided at one time interval vs SPT provided at a different time interval

Population: Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
CD009376.PUB2 (current) · 1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
no estimate extracted0 studiesNo studies

SPT using one technique or appliance for mechanical root debridement vs SPT using a different technique or appliance for mechanical root debridement

Population: Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
CD009376.PUB2 (current) · 1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
no estimate extracted0 studiesNo studies

Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone

Population: Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
CD009376.PUB2 (current) · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Pocket depth (mm)
12 months
MD -0.10 [-0.59, 0.39]
4.3 mm (control) vs PD was 0.10 mm lower (from 0.59 lower to 0.39 higher)
1 study · 51 participantsLow
Downgraded: risk of bias, imprecision
Bleeding on probing (ratios)
12 months
OR 0.45 [0.14, 1.52]1 study · 50 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
12 months
See comment. Killeen 2016 reported no adverse events at follow-up examinations in either study arm. Tonetti 2012 reported that there were no serious adverse events.2 studies · 251 participantsUngraded
Clinical attachment level (mm)
12 months
MD 0.10 [-0.42, 0.62]
Change score 4.6 mm (control) vs Change score was 0.10 mm higher (from 0.42 lower to 0.62 higher)
1 study · 53 participantsLow
Downgraded: risk of bias, imprecision
Tooth loss
Not measured0 studiesNo studies

Photodynamic therapy plus mechanical debridement vs Mechanical debridement alone

Population: Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
CD009376.PUB2 (current) · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Bleeding on probing
12 months
Not measured in usable way (Lulic 2009 reported only the percentage of sites with bleeding, with no participant-based measures)1 studyUngraded
Clinical attachment level (mm)
12 months
MD -0.97 [-3.51, 1.57]
7.76 mm (control) vs 0.97 mm lower (from 3.51 lower to 1.57 higher)
1 study · 10 participantsVery low
Downgraded: risk of bias, imprecision
Tooth loss
Not measured0 studiesNo studies
Adverse events
Not measured0 studiesNo studies
Probing pocket depth (mm)
12 months
MD -0.09 [-1.41, 1.23]
5.9 mm (control) vs 0.09 mm lower (from 1.41 lower to 1.23 higher)
1 study · 10 participantsVery low
Downgraded: risk of bias, imprecision

SPT provided by a periodontist/specialist vs SPT provided by a general dental practitioner (conventional dental care)

Population: Adults (18 years or older) previously treated for periodontal disease
CD009376 · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Tooth loss
no estimate extractedNRNo studies
Clinical attachment level (CAL)
no estimate extractedNRNo studies
Probing pocket depth (PPD)
no estimate extractedNRNo studies
Bleeding on probing (BoP)
no estimate extractedNRNo studies

Supportive periodontal therapy (SPT) vs No SPT / monitoring only

Population: Adults (18 years or older) previously treated for periodontal disease
CD009376 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
no estimate extractedNRNo studies

SPT provided at one time interval (3, 6 or 12 months) vs SPT provided at a different time interval

Population: Adults (18 years or older) previously treated for periodontal disease
CD009376 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
no estimate extractedNRNo studies

SPT with one type of mechanical root debridement vs SPT with a different type of mechanical root debridement

Population: Adults (18 years or older) previously treated for periodontal disease
CD009376 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
no estimate extractedNRNo studies

SPT with adjunctive treatment (oral hygiene reinforcement or local antimicrobials) vs SPT without adjunctive treatment (mechanical debridement alone)

Population: Adults (18 years or older) previously treated for periodontal disease
CD009376 · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Bleeding on probing (BoP)
no estimate extractedNRNo studies
Clinical attachment level (CAL)
no estimate extractedNRNo studies
Probing pocket depth (PPD)
no estimate extractedNRNo studies
Tooth loss
no estimate extractedNRNo studies