Death (all causes) · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors leads to lower all‐cause death median compared with placebo (high certainty).
All‐cause mortality · people with sickle cell disease
AEs · chronic pain (excluding headache) in adults
no estimate extracted
0 studies · 0 participants
GRADE not reported
RR 6 [2.2, 16.4]
1 study · 140 participants
Very low
no estimate extracted
8 studies · 1314 participants
Very low
Reduction in pain intensity · chronic pain (excluding headache) in adults
It is very uncertain whether CBT changes pain intensity (number of people with ≥ 30 % improvement)… compared with TAU (at follow‐up) (very low certainty).
Respiratory‐related hospital admissions · patients with chronic obstructive pulmonary disease
It is very uncertain whether self‐management interventions changes respiratory‐related hospital admissions compared with usual care (very low certainty).
Respiratory‐related mortality · patients with chronic obstructive pulmonary disease
Self‐management interventions showed no clear difference in respiratory‐related mortality compared with usual care (low certainty).
All‐cause mortality · patients with chronic obstructive pulmonary disease
Self‐management interventions showed no clear difference in all‐cause mortality compared with usual care (low certainty).
Hospital admissions · patients with chronic obstructive pulmonary disease
Self‐management interventions showed no clear difference in all‐cause hospital admissions compared with usual care (moderate certainty).
COPD exacerbations · patients with chronic obstructive pulmonary disease
Withdrawals due to adverse events · people with chronic gout
Skim milk enriched with GMP/G600 showed no clear difference in study withdrawals due to adverse events compared with skim milk, plus lactose powder (low certainty).
Joint pain reduction ‐ not reported · people with chronic gout
All‐cause mortality
HbA1c (%)
Health‐related quality of life
HbA1c (%)
All‐cause mortality
0.14 [0, 6.98]
8 studies · 2175 participants
Moderate
Peto OR 1.06 [0.62, 1.82]
14 studies · 6173 participants
Low
Adverse events · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Overall survival · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Progression‐free survival · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Quality of life · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found