Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

62 questions · 73 findings · 26 reviews · Anaesthesia · Headline outcomes only

No studies found 5 · 6.8%GRADE not reported 4 · 5.5%Very low 21 · 28.8%Low 28 · 38.4%Moderate 12 · 16.4%High 3 · 4.1%

Intervention not reported

Hypotension (within 30 days; as defined by study authors, minimum systolic blood pressure < 90 mmHg or requiring medication) · adults undergoing cardiac surgery under general anaesthesia

The intervention showed no clear difference in hypotension (within 30 days; as defined by study authors, minimum… (low certainty).

1 finding from 1 review

Perioperative beta‐blockers vs placebo or usual care

Hypotension · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers probably leads to higher hypotension (within 30 days; as defined by study authors, minimum… compared with placebo or standard care (moderate certainty).

1 finding from 1 review

Alpha2‐adrenergic agonist vs control

Hypotension (requiring treatment with inotropes or vasopressors during the period of study drug administration) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists showed no clear difference in hypotension (requiring treatment with inotropes or vasopressors… compared with control (low certainty).

1 finding from 1 review

Isopropyl alcohol vs usual care

Adverse events (common reactions to aromatherapy include skin rashes, dyspnoea, headache, cardiac arrhythmias, hypotension, hypertension or dizziness) · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

The review found no eligible studies for this question.

1 finding from 1 review

Isopropyl alcohol vs Normal saline

Adverse events (common reactions to aromatherapy include skin rashes, dyspnoea, headache, cardiac arrhythmias, hypotension, hypertension or dizziness) · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

The review found no eligible studies for this question.

1 finding from 1 review