Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

116 questions · 120 findings · 11 reviews · Neuromuscular · Headline outcomes only

No studies found 25 · 20.8%GRADE not reported 5 · 4.2%Very low 35 · 29.2%Low 20 · 16.7%Moderate 27 · 22.5%High 8 · 6.7%

Corticosteroids vs placebo

Improvement in sensory nerve function at 1 year · people with nerve damage (< 6 months' duration) in leprosy

Corticosteroids showed no clear difference in improvement in sensory nerve function at 1 year Defined as a… compared with placebo (moderate certainty).

1 finding from 1 review

Corticosteroids vs placebo

Change in nerve pain and in nerve tenderness at 1 year ‐ not reported · people with nerve damage (6 to 24 months' duration) in leprosy

The review found no eligible studies for this question.

1 finding from 1 review

Corticosteroids vs placebo

Adverse effects requiring withdrawal/discontinuation of study medication · people with nerve damage (6 to 24 months' duration) in leprosy

Corticosteroids showed no clear difference in adverse events Assessed as adverse events requiring withdrawal of… compared with placebo (moderate certainty).

1 finding from 1 review