Cochrane · systematic review · CD001942

Corticosteroids for Bell's palsy (idiopathic facial paralysis)

Madhok, VB, Gagyor, I, Daly, F, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 2 · 50%High 1 · 25%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Corticosteroids compared to placebo or no treatment for Bell's palsy

Population: people with Bell's palsy
4 questions
OutcomeEffectEvidenceStatus / GRADE
Incomplete recovery ≥ 6 months after randomisation House‐Brackmann grading system and Sunnybrook scale
Corticosteroids vs placebo or no treatment
RR 0.63 [0.5, 0.8]7 studies · 895 participantsHigh
Cosmetically disabling persistent sequelae ≥ 6 months after randomisation Clinical assessment
Corticosteroids vs placebo or no treatment
RR 0.96 [0.4, 2.29]2 studies · 75 participantsLow
Downgraded: imprecision, indirectness, publication bias
Motor synkinesis and crocodile tears Clinical assessment
Corticosteroids vs placebo or no treatment
RR 0.64 [0.45, 0.91]3 studies · 485 participantsModerate
Downgraded: imprecision, indirectness, publication bias
Adverse effects
Corticosteroids vs placebo or no treatment
RR 1.04 [0.71, 1.51]3 studies · 715 participantsModerate
Downgraded: imprecision, indirectness, publication bias