Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with a serious adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with ≥ 1 adverse event following a single dose, and after 3 to 5 days · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Participants with a serious adverse event following a single dose, and after 3 to 5 days · adults with moderate or severe acute postoperative pain
1 finding from 1 review
Ambulation · adults with metastatic extradural spinal cord compression (poor prognosis with visceral metastasis, and no spinal instability or bony…
Single‐fraction radiotherapy (8 Gy) showed no clear difference in ambulation One month after radiation compared with short‐course radiotherapy (16 Gy (moderate certainty).
1 finding from 1 review
Survival · adults with metastatic extradural spinal cord compression (poor prognosis with visceral metastasis, and no spinal instability or bony…
1 finding from 1 review
Reduction in analgesic and narcotic use One month after radiation · adults with metastatic extradural spinal cord compression (poor prognosis with visceral metastasis, and no spinal instability or bony…
Single‐fraction radiotherapy (8 Gy) showed no clear difference in reduction in analgesic and narcotic use One month after radiation compared with short‐course radiotherapy (16 Gy (moderate certainty).
1 finding from 1 review
Urinary continence One month after radiation · adults with metastatic extradural spinal cord compression (poor prognosis with visceral metastasis, and no spinal instability or bony…
Single‐fraction radiotherapy (8 Gy) showed no clear difference in urinary continence One month after radiation compared with short‐course radiotherapy (16 Gy (moderate certainty).
1 finding from 1 review
Local recurrence · adults with metastatic extradural spinal cord compression (poor prognosis with visceral metastasis, and no spinal instability or bony…
Single‐fraction radiotherapy (8 Gy) showed no clear difference in local recurrence MRI: compared with short‐course radiotherapy (16 Gy (low certainty).
1 finding from 1 review
Adverse events Grade 3 oesophagitis, diarrhoea and nausea · adults with metastatic extradural spinal cord compression (poor prognosis with visceral metastasis, and no spinal instability or bony…
Single‐fraction radiotherapy (8 Gy) showed no clear difference in adverse events Grade 3 oesophagitis, diarrhoea and nausea compared with short‐course radiotherapy (16 Gy (moderate certainty).
1 finding from 1 review
Quality of life · adults with metastatic extradural spinal cord compression (poor prognosis with visceral metastasis, and no spinal instability or bony…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ambulation · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
It is very uncertain whether laminectomy plus radiotherapy changes ambulation At four months compared with radiotherapy (very low certainty).
1 finding from 1 review
Survival At four months · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
It is very uncertain whether laminectomy plus radiotherapy changes survival At four months compared with radiotherapy (very low certainty).
1 finding from 1 review
Reduced use of analgesics · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
It is very uncertain whether laminectomy plus radiotherapy changes reduction in analgesic use compared with radiotherapy (very low certainty).
1 finding from 1 review