Question · asked by 1 review

Laminectomy plus radiotherapy vs radiotherapy: Reduced use of analgesics

It is very uncertain whether laminectomy plus radiotherapy changes reduction in analgesic use compared with radiotherapy (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Laminectomy plus radiotherapy vs radiotherapy
Reduction in analgesic use · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
It is very uncertain whether laminectomy plus radiotherapy changes reduction in analgesic use compared with radiotherapy (very low certainty).
Interventions for the treatment of metastatic extradural spinal cord compression in adults (2015) · Cochrane Headline outcomes only
RR 0.88 [0.42, 1.81]1 study · 26 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for the treatment of metastatic extradural spinal cord compression in adults
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.