Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

36 questions · 36 findings · 4 reviews

No studies found 7 · 19.4%GRADE not reported 1 · 2.8%Very low 9 · 25%Low 16 · 44.4%Moderate 0 · 0%High 3 · 8.3%

SSRIs or SNRIs vs amitriptyline

Participants who withdraw because of an adverse event or any other reason · patients for whom migraine preventive interventions are indicated

SSRIs or SNRIs showed no clear difference in withdrawn (for any reasons and due to adverse events) compared with amitriptyline (low certainty).

1 finding from 1 review