Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

36 questions · 39 findings · 11 reviews · ENT

No studies found 17 · 43.6%GRADE not reported 0 · 0%Very low 1 · 2.6%Low 16 · 41%Moderate 5 · 12.8%High 0 · 0%

Antihistamines vs scopolamine

Physiological measures: core temperature and gastric tachyarrhythmia (electrogastrography) · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs acupuncture

Physiological measures: heart rate, core temperature and gastric tachyarrhythmia (electrogastrography) · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: 1. Sedation · patients with motion sickness

Antihistamines may leads to higher adverse effects: sedation Assessed by: adverse effect questionnaire… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: impaired cognition Assessed by: adverse effect questionnaire (presence or absence given numerical values) · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: impaired cognition Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: blurred vision Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Caloric extent of recovery (improvement as a % in lateralisation of electronystagmography on caloric testing) · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
2 findings from 1 review

Corticosteroids vs placebo

Complete caloric recovery · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)

Corticosteroids may leads to higher complete caloric recovery compared with placebo (low certainty).

2 findings from 1 review