Serological cure (4‐fold decrease or greater in non‐treponemal tests titre) · newborns with congenital syphilis
Antibiotic treatment (benzathine penicillin) showed no clear difference in serological cure (4‐fold decrease or greater in non‐treponemal tests… compared with any other antibiotic (procaine benzylpenicillin) (moderate certainty).
1 finding from 1 review
Minor adverse events · newborns with congenital syphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neonatal death rate due congenital syphilis · newborns with congenital syphilis
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Neonatal death rate due to any cause · newborns with congenital syphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Absence of clinical manifestations of congenital syphilis during · newborns with congenital syphilis
Antibiotic treatment (benzathine penicillin) showed no clear difference in absence of clinical manifestations of congenital syphilis during compared with any other antibiotic (procaine benzylpenicillin) (high certainty).
1 finding from 1 review
HIV seroconversion ‐ penicillin vs single‐dose azithromycin · patients with syphilis
1 finding from 1 review
HIV seroconversion ‐ penicillin vs two‐dose azithromycin · patients with syphilis
1 finding from 1 review
Serological cure assessed by decrease in the CSF VDRL titre · people with neurosyphilis
1 finding from 1 review
Clinical cure assessed by RPR decrease · people with neurosyphilis
1 finding from 1 review
Adverse events Any untoward medical occurrence regarding medications · people with neurosyphilis
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Very low
Recurrence of neurosyphilis · people with neurosyphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to recovery · people with neurosyphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · people with neurosyphilis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment withdrawal · people with neurosyphilis
It is very uncertain whether ceftriaxone changes withdrawals compared with penicillin G (very low certainty).
1 finding from 1 review