Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

25 questions · 25 findings · 6 reviews · Emergency and Critical Care

No studies found 1 · 4%GRADE not reported 2 · 8%Very low 8 · 32%Low 7 · 28%Moderate 7 · 28%High 0 · 0%

Oxygenation vs no oxygenation during the apnoeic period preceding intubation

Incidence of severe hypoxaemia (SpO2 < 80%) · people requiring tracheal intubation

Oxygenation showed no clear difference in incidence of severe hypoxaemia (SpO2 < 80%) compared with no oxygenation during the apnoeic period preceding intubation (low certainty).

1 finding from 1 review

Oxygenation vs no oxygenation during the apnoeic period preceding intubation

Hypoxaemia · people requiring tracheal intubation

Oxygenation showed no clear difference in incidence of hypoxaemia (SpO2 < 93%) compared with no oxygenation during the apnoeic period preceding intubation (low certainty).

1 finding from 1 review

Oxygenation vs no oxygenation during the apnoeic period preceding intubation

First‐pass success of cannulation · people requiring tracheal intubation

Oxygenation showed no clear difference in first pass success rate compared with no oxygenation during the apnoeic period preceding intubation (moderate certainty).

1 finding from 1 review

Oxygenation vs no oxygenation during the apnoeic period preceding intubation

All‐cause mortality · people requiring tracheal intubation

Oxygenation showed no clear difference in mortality compared with no oxygenation during the apnoeic period preceding intubation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: all ECMO studies · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to lower all‐cause mortality: all ECMO studies compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: VV ECMO subgroup · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to lower all‐cause mortality: VV ECMO subgroup compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: VA ECMO subgroup · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in all‐cause mortality: VA ECMO subgroup compared with conventional care (low certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality at 6 months (subgroup) · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in all‐cause mortality: ECPR subgroup compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

Major hemorrhage · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to higher major hemorrhage: all available studies compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

Neurologic injury: all available studies · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in neurologic injury: all available studies compared with conventional care (moderate certainty).

1 finding from 1 review

Higher vs lower FiO2 or targets of arterial oxygenation

All‐cause mortality: range 1 mo to 1 y · adults admitted to the ICU

It is very uncertain whether higher changes all‐cause mortality: range 1 mo to 1 y compared with lower FiO2 or targets of arterial oxygenation (very low certainty).

1 finding from 1 review

Higher vs lower FiO2 or targets of arterial oxygenation

Proportion of participants with 1 or more serious adverse events according to International Conference on Harmonisation Good Clinical Practice (ICH‐GCP) · adults admitted to the ICU

It is very uncertain whether higher changes proportion of participants with ≥ 1 serious adverse events according… compared with lower FiO2 or targets of arterial oxygenation (very low certainty).

1 finding from 1 review