Cochrane · systematic review · CD010381
Extracorporeal membrane oxygenation for critically ill adults
Burrell, A, Kim, J, Alliegro, P, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 5 · 83.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) compared to conventional care for severe cardiorespiratory failure and cardiac arrest
Population: severe cardiorespiratory failure and cardiac arrest
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality: all ECMO studies Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs conventional care | RR 0.8 [0.7, 0.92] | 5 studies · 756 participants | Moderate Downgraded: inconsistency, indirectness |
All‐cause mortality: VV ECMO subgroup Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs conventional care | RR 0.77 [0.62, 0.96] | 2 studies · 429 participants | Moderate Downgraded: indirectness |
All‐cause mortality: VA ECMO subgroup Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs conventional care | RR 0.5 [0.18, 1.41] | 1 study · 42 participants | Low Downgraded: risk of bias, imprecision |
All‐cause mortality: ECPR subgroup Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs conventional care | RR 0.76 [0.52, 1.13] | 2 studies · 285 participants | Moderate Downgraded: risk of bias |
Major hemorrhage: all available studies Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs conventional care | RR 3.32 [1.9, 5.82] | 4 studies · 577 participants | Moderate Downgraded: risk of bias, imprecision |
Neurologic injury: all available studies Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs conventional care | RR 2.83 [0.36, 22.42] | 2 studies · 286 participants | Moderate Downgraded: imprecision |