Cochrane · systematic review · CD013558
Oxygenation during the apnoeic phase preceding intubation in adults in prehospital, emergency department, intensive care and operating theatre environments
White, LD, Vlok, RA, Thang, CYC, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 12.5%Ungraded 1 · 12.5%Very low 0 · 0%Low 5 · 62.5%Moderate 1 · 12.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Oxygenation versus no oxygenation during the apnoeic period preceding intubation
Population: people requiring tracheal intubation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Hospital stay Oxygenation vs no oxygenation during the apnoeic period preceding intubation | no estimate extracted | NR | No studies |
Incidence of severe hypoxaemia (SpO2 < 80%) Oxygenation vs no oxygenation during the apnoeic period preceding intubation | RR 0.86 [0.66, 1.11] | 15 studies · 1802 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Incidence of hypoxaemia (SpO2 < 93%) Oxygenation vs no oxygenation during the apnoeic period preceding intubation | RR 0.58 [0.23, 1.46] | 3 studies · 489 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Lowest recorded SpO2 (%) Oxygenation vs no oxygenation during the apnoeic period preceding intubation | no estimate extracted | 15 studies · 1525 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
ICU stay (days) Oxygenation vs no oxygenation during the apnoeic period preceding intubation | no estimate extracted | 5 studies · 815 participants | Low Downgraded: risk of bias, imprecision |
First pass success rate Oxygenation vs no oxygenation during the apnoeic period preceding intubation | RR 1 [0.93, 1.08] | 8 studies · 826 participants | Moderate Downgraded: risk of bias |
Adverse eventse Oxygenation vs no oxygenation during the apnoeic period preceding intubation | no estimate extracted | 10 studies · 997 participants | Ungraded |
Mortality Oxygenation vs no oxygenation during the apnoeic period preceding intubation | RR 0.84 [0.7, 1] | 6 studies · 1015 participants | Low Downgraded: risk of bias, imprecision, indirectness |